Evidence map›Paper›PMID 41345604›Full record

Trial reportBMC oral health2025

Effectiveness of the "CEME" oral health intervention program for preventing stroke-associated pneumonia in patients with post-stroke dysphagia: a randomized controlled trial.

Qian Li, YanLing Li, Yan Tian, Juan Xiang, Ting Xu, EnJie Tang, Jing He

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Qian LiDepartment of Neurology, Second Affiliated Hospital of Army Military Medical University, Chongqing, 400037, China.
YanLing LiDepartment of Neurology, Second Affiliated Hospital of Army Military Medical University, Chongqing, 400037, China.
Yan TianDepartment of Neurology, Second Affiliated Hospital of Army Military Medical University, Chongqing, 400037, China.
Juan XiangDepartment of Neurology, Second Affiliated Hospital of Army Military Medical University, Chongqing, 400037, China.
Ting XuDepartment of Neurology, Second Affiliated Hospital of Army Military Medical University, Chongqing, 400037, China.
EnJie TangDepartment of Neurology, 925 Hospital of PLA Joint Logistics Support Force, Guizhou, 550009, China.
Jing HeDepartment of Hospital-Acquired Infection Control, Second Affiliated Hospital of Army Military Medical University, Chongqing, 400037, China. hejing55571@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundPneumonia is common among post-stroke dysphagia (PSD) patients, especially in the week following a stroke; pneumonia may prolong hospital stays or lead to mortality. We examined whether a tailored "CEME" (oral cleaning, oral motor exercises, Chinese acupoint and salivary gland massage, and safe-swallowing education) oral health intervention program could improve swallowing function and oral health and reduce the incidence of stroke-associated pneumonia (SAP) in PSD patients.

methodsWe conducted an assessor-blinded randomized controlled trial in a tertiary hospital in China. Eighty-four PSD patients were recruited and randomly assigned to either the control group (n = 42) or the experimental group (n = 42). The control group received conventional oral care, whereas those in the experimental group participated in the "CEME" oral health intervention program, which included oral cleaning, oral motor exercises, Chinese acupoint and salivary gland massage, and safe-swallowing education. Outcome measures were conducted on day 7 of the implementation of the intervention, including stroke-associated pneumonia incidence, swallowing function (measured via the Water Swallowing Test (WST) and the Functional Oral Intake Scale [FOIS]), overall oral health (measured via the Oral Health Assessment Tool [OHAT]), salivary secretion status (measured via the modified Schirmer test [MST]), oral hygiene status (measured via the Plaque Index [PI]), and stroke severity (assessed via the National Institute of Health Stroke Scale [NIHSS]).

resultsThe incidence of SAP in the experimental group was 10.26% (4/39), lower than the corresponding figure in the control group of 32.43% (12/37) (P < 0.05); furthermore, the WST grades, OHAT scores, and Plaque Index exhibited by the experimental group were better than the control group (P < 0.05). No significant differences were observed in FOIS grades, MST or NIHSS scores (P > 0.05).

conclusionThe tailored CEME intervention effectively reduced SAP incidence in PSD patients while concomitantly improving oral health and water swallowing function.

trial registrationChiCTR2300074510, registered on August 08, 2023.

Indexed as

Deglutition DisordersOral HealthOral HygienePneumoniaPneumonia, AspirationStrokeAgedChinaDeglutitionFemaleHumansMaleMassageMiddle AgedStroke RehabilitationInterventionOral healthPost-stroke dysphagiaStrokeStroke-associated pneumonia

Identifiers

PMID41345604
PMCPMC12676861

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.