Evidence map›Paper›PMID 41345587›Full record

ArticleBMC surgery2025

Short-term outcomes of atrial septal defect repair via right axillary incision in children: a single-center propensity-matched analysis.

Jingyu Liu, Zhuheng Wu, Lin Xie, Xingyu Zheng, Ke Lin

Abstract readComparative Study
In one paragraph

Article in BMC surgery, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

5 authors.

Jingyu LiuDepartment of Cardiovascular Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China.
Zhuheng WuDepartment of Cardiovascular Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China.
Lin XieDepartment of Cardiovascular Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China.
Xingyu ZhengDepartment of Cardiovascular Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China.
Ke LinDepartment of Cardiovascular Surgery, West China Hospital, Sichuan University, Chengdu, Sichuan, 610041, China. edidian@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTo compare the short-term outcomes of atrial septal defect (ASD) repair via right axillary incision (RAI) versus median sternotomy (MS) in children.

methodsThis single-center, retrospective, controlled study aimed to compare the short-term outcomes of ASD repair performed via right axillary incision versus median sternotomy in children. The primary endpoint was the incidence of perioperative adverse events.

resultsA total of 162 pediatric patients (< 18 years) were included in this study, with 80 patients in the RAI group and 82 patients in the MS group. The overall mean age of enrolled patients was 4.9 years, and 73 (45.1%) patients of them were male. The RAI group had less intraoperative bleeding (P < 0.001), shorter ventilation time (P < 0.001), and lower drainage volume in 24 h (P < 0.001), with longer cardiopulmonary bypass time compared to the MS group (P = 0.004). The overall median follow-up time was 9.0 (7.0-15.0) months. There were no statistically significant differences between two groups in the incidence of perioperative adverse events [37(46.3%) vs. 42 (51.2%); P = 0.527]. During propensity score matching, 47 patients from the RAI group and 52 from the MS group were successfully matched. After match, the RAI group exhibited longer cardiopulmonary bypass time (P = 0.008), less ventilation time (P = 0.043) and lower drainage volume in 24 h (P < 0.001). No patient from either group still had residual shunt during the last follow-up. 2 (2.4%) patients in the MS group developed new-onset arrhythmias after surgery. Weight and age were identified as potential predictors in assisting the decision-making between RAI and MS approaches.

conclusionThe RAI approach is a safe and feasible alternative to MS for pediatric ASD repair, with comparable short-term outcomes. Although associated with longer CPB time, RAI may reduce surgical trauma in selected patients. Younger age and lower body weight may serve as preliminary indicators for RAI suitability.

Indexed as

AxillaCardiac Surgical ProceduresHeart Septal Defects, AtrialSternotomyAdolescentChildChild, PreschoolFemaleHumansInfantMalePostoperative ComplicationsPropensity ScoreRetrospective StudiesTime FactorsTreatment OutcomeAtrial septal defectMedian sternotomyRight axillary incisionShort-term outcome

Identifiers

PMID41345587
PMCPMC12781798

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.