ArticleScientific reports2025
Smart photonic crystal fiber optical sensor for tuberculosis detection with machine learning integration.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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7 authors.
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Abstract
One of the most common infectious disease-related causes of death globally, particularly in low- and middle-income nations, persists: tuberculosis. At a manifestation of globalization, causes of death keep growing. As it happens, we have developed a sensor that quickly recognizes tuberculosis. The sensor operates in the (1-2 THz) frequency band, resulting in exemplary recognition and accuracy. Our present work asserts the design and numerical analysis of a hexagonal hollow-core photonic crystal fiber (HC-PCF) sensor for detecting tuberculosis (TB) cells adopting the finite element method (FEM) in COMSOL Multiphysics 6.1. This work highlights the synergy between advanced photonic sensor design and intelligent data analytics in next-generation healthcare technologies. The sensor operates at 1.6 THz and is optimized to achieve high relative sensitivity (RS), low confinement loss (CL), and minimal effective material loss (EML), critical parameters for effective biosensing. The proposed PCF has a maximum Relative Sensitivity of 95.28%, 95.34%, 95.41%, 95.46% & 95.53%, corresponding to refractive indexes (RI) of n = 1.345, 1.346, 1.347, 1.348 and 1.349; which are characteristic of TB-infected biological samples. CL values fall from 1.254 × 10
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