Evidence map›Paper›PMID 41345401›Full record

ArticleNature communications2025

Crystal structures and snapshots along Tpt1-catalyzed phosphate transfer from nucleic acid to NAD

Chulei Cao, Jie Yang, Weizhen Zhang, Jiaqin Chen, Yanqing Gao, Yuqi Yao, Yixi Zhang, Huili Li, Linxi Li, Zhaorong Luo and 8 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Chulei Cao *State Key Laboratory of Genetics and Development of Complex Phenotypes, Department of Biochemistry and Biophysics, School of Life Sciences, Fudan University, Shanghai, China.
Jie Yang *State Key Laboratory of Genetics and Development of Complex Phenotypes, Department of Biochemistry and Biophysics, School of Life Sciences, Fudan University, Shanghai, China.
Weizhen Zhang *State Key Laboratory of Genetics and Development of Complex Phenotypes, Department of Biochemistry and Biophysics, School of Life Sciences, Fudan University, Shanghai, China.ORCID http://orcid.org/0000-0002-7542-2772
Jiaqin ChenState Key Laboratory of Genetics and Development of Complex Phenotypes, Department of Biochemistry and Biophysics, School of Life Sciences, Fudan University, Shanghai, China.
Yanqing GaoState Key Laboratory of Genetics and Development of Complex Phenotypes, Department of Biochemistry and Biophysics, School of Life Sciences, Fudan University, Shanghai, China.ORCID http://orcid.org/0000-0002-0989-0631
Yuqi YaoState Key Laboratory of Genetics and Development of Complex Phenotypes, Department of Biochemistry and Biophysics, School of Life Sciences, Fudan University, Shanghai, China.
Yixi ZhangState Key Laboratory of Genetics and Development of Complex Phenotypes, Department of Biochemistry and Biophysics, School of Life Sciences, Fudan University, Shanghai, China.
Huili LiState Key Laboratory of Genetics and Development of Complex Phenotypes, Department of Biochemistry and Biophysics, School of Life Sciences, Fudan University, Shanghai, China.
Linxi LiState Key Laboratory of Genetics and Development of Complex Phenotypes, Department of Biochemistry and Biophysics, School of Life Sciences, Fudan University, Shanghai, China.
Zhaorong LuoState Key Laboratory of Genetics and Development of Complex Phenotypes, Department of Biochemistry and Biophysics, School of Life Sciences, Fudan University, Shanghai, China.
Chenxi WangState Key Laboratory of Genetics and Development of Complex Phenotypes, Department of Biochemistry and Biophysics, School of Life Sciences, Fudan University, Shanghai, China.
Guangli TangState Key Laboratory of Genetics and Development of Complex Phenotypes, Department of Biochemistry and Biophysics, School of Life Sciences, Fudan University, Shanghai, China.
Ruixue CuiDepartment of Geriatrics, Medical center on Aging of Shanghai Ruijin Hospital, Shanghai Jiaotong University school of Medicine, Shanghai, China.
Hehua LiuState Key Laboratory of Genetics and Development of Complex Phenotypes, Department of Biochemistry and Biophysics, School of Life Sciences, Fudan University, Shanghai, China.
Qiyao WangState Key Laboratory of Bioreactor Engineering, East China University of Science and Technology, Shanghai, China.
Zhen HuangSzostak Large Nucleic Acids Institute and SeNA Research Institute, School of Life Sciences, Hubei University, Wuhan, Hubei, China.ORCID http://orcid.org/0000-0002-8640-3227
Jinbiao MaState Key Laboratory of Genetics and Development of Complex Phenotypes, Department of Biochemistry and Biophysics, School of Life Sciences, Fudan University, Shanghai, China.ORCID http://orcid.org/0000-0002-0232-1786
Jianhua GanState Key Laboratory of Genetics and Development of Complex Phenotypes, Department of Biochemistry and Biophysics, School of Life Sciences, Fudan University, Shanghai, China. ganjhh@fudan.edu.cn.ORCID http://orcid.org/0000-0002-8438-8852

Funding

National Natural Science Foundation of China (National Science Foundation of China) 32371252, 32171197, and 32571387Natural Science Foundation of Shanghai (Natural Science Foundation of Shanghai Municipality) 25ZR1402332
6 · The paper itself

Abstract

Tpt1/TRPT1/KptA family proteins are evolutionarily conserved in all three domains of life. In fungi and plants, Tpt1 transfers 2'-PO

Indexed as

NADNucleic AcidsPhosphatesAdenosine Diphosphate RiboseBiocatalysisCatalysisCrystallography, X-RayModels, MolecularRNA, TransferAdenosine Diphosphate RiboseNADNucleic AcidsPhosphatesRNA, Transfer

Identifiers

PMID41345401
PMCPMC12678800

What OpenQuestion holds

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LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.