Evidence map›Paper›PMID 41345361›Full record

ArticleWorld journal of urology2025

Anatomical and intraoperative predictors of surgical complications after distal hypospadias repair with foreskin reconstruction: a prospective study.

Maria Escolino, Claudia Di Mento, Francesca Carraturo, Annalisa Chiodi, Fulvia Del Conte, Giovanni Esposito, Vincenzo Coppola, Maria Sofia Caracò, Benedetta Cesaro, Maria Luisa Pirone and 1 more

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Article in World journal of urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed
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1 · What the graph read from it

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3 · Its place in the literature

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1 citing paper in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

11 authors.

Maria EscolinoDivision of Pediatric Surgery, Federico II University Hospital, Via Pansini, 5, Naples, 80131, Italy. x.escolino@libero.it.
Claudia Di MentoDivision of Pediatric Surgery, Federico II University Hospital, Via Pansini, 5, Naples, 80131, Italy.
Francesca CarraturoDivision of Pediatric Surgery, Federico II University Hospital, Via Pansini, 5, Naples, 80131, Italy.
Annalisa ChiodiDivision of Pediatric Surgery, Federico II University Hospital, Via Pansini, 5, Naples, 80131, Italy.
Fulvia Del ConteDivision of Pediatric Surgery, Federico II University Hospital, Via Pansini, 5, Naples, 80131, Italy.
Giovanni EspositoCEINGE Advanced Biotechnologies, Naples, Italy.
Vincenzo CoppolaDivision of Pediatric Surgery, Federico II University Hospital, Via Pansini, 5, Naples, 80131, Italy.
Maria Sofia CaracòDivision of Pediatric Surgery, Federico II University Hospital, Via Pansini, 5, Naples, 80131, Italy.
Benedetta CesaroDivision of Pediatric Surgery, Federico II University Hospital, Via Pansini, 5, Naples, 80131, Italy.
Maria Luisa PironeDivision of Pediatric Surgery, Federico II University Hospital, Via Pansini, 5, Naples, 80131, Italy.
Ciro EspositoDivision of Pediatric Surgery, Federico II University Hospital, Via Pansini, 5, Naples, 80131, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis study aimed to evaluate anatomical and intraoperative risk factors predicting complications following distal hypospadias repair with foreskin reconstruction in pediatric patients.

methodsA prospective analysis was conducted on all patients with distal hypospadias undergoing tubularized incised plate urethroplasty (TIPU) with foreskin reconstruction over a 2-year period. Intraoperative measurements-stretched penile length, glans width, glans groove width, meatal position, ischemic time and preputial symmetry-were recorded. Postoperative complications and reoperations were analyzed through multivariate logistic regression to determine independent predictors.

resultsThe patient cohort included 71 operated boys. Median patient age was 2.4 years (range 1-9.1), and median follow-up was 12.8 months. The most frequent complications were foreskin dehiscence (12.7%), non-retractile foreskin (12.7%), meatal/urethral stenosis (11.3%), and urethrocutaneous fistula (7.0%). Prolonged ischemic time (> 60 min) independently predicted foreskin dehiscence (p = 0.03) and reoperation (p = 0.003). Shorter PL (≤ 3 cm) was associated with higher stenosis rates, while more proximal distal meatal position (subcoronal/midpenile) increased the risk of foreskin dehiscence (p = 0.0006), fistula (p = 0.007), and reoperation (p = 0.02). Age > 2 years significantly predicted meatal/urethral stenosis (p = 0.01) and reoperation (p = 0.001). Preputial asymmetry correlated with foreskin dehiscence (p = 0.006), whereas glans width and groove width showed no significant associations (p > 0.05).

conclusionProlonged ischemic time, shorter penile length, more proximal distal meatal position, asymmetric prepuce and older age at surgery are independent predictors of postoperative complications and reoperations after distal hypospadias repair with foreskin reconstruction. Careful preoperative assessment, minimizing intraoperative ischemic duration, and considering earlier surgery before 2 years of age may improve both functional and cosmetic outcomes.

Indexed as

ForeskinHypospadiasPlastic Surgery ProceduresPostoperative ComplicationsUrologic Surgical Procedures, MaleChildChild, PreschoolHumansInfantMalePenisProspective StudiesReoperationRisk FactorsUrethraAnatomyChildrenComplicationsHypospadiasRisk factorsUrethroplasty

Identifiers

PMID41345361
PMCPMC12678460

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