ArticleAesthetic plastic surgery2026
Analysis in 3D of Hybrid Injectable Combining Hyaluronic Acid and Calcium Hydroxyapatite: Prospective Study.
Article in Aesthetic plastic surgery, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- Clinical Outcomes of HArmonyCa® in South American Patients: A Case Series Using Vectra 3D Technology.Aesthetic plastic surgery · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAging is a process that has a major impact nowadays, influencing functional and esthetic aspects, and the population's self-esteem. Thus, researchers and companies are investing significantly in studies to control the effects of this process, especially on the face. PURPOSE: To analyze the volume gain and facial lifting effect in three dimensions after HArmonyCa
methodsEight female patients with a mean age of 47 years received 1.25 ml of HArmonyCa
resultsVolumetric analysis showed a greater volume at the immediate, 30-day, and 90-day post-procedure periods than in the pre-procedure in the temple region (P = 0.002) and pre-jowl (P = 0.001). In the zygomatic arch regions (P = 0.004) and mandibular branch (P = 0.016), a greater volume was noticed at the immediate and 90-day post-procedure periods than in the pre-procedure. In vector analysis, yellow, orange, and red arrows were higher and predominant in the middle third region of the face, posterior to the imaginary line that connects the main ligaments of the face. The red arrows, which indicate the greatest tissue displacement, were measured, and a statistically significant difference was shown between the pre-procedure and the other periods studied (P<0.0001).
conclusionThe hybrid injectable studied caused an immediate lifting effect associated with progressive tissue displacement, reducing skin sagging. LEVEL OF EVIDENCE I: This journal requires that authors assign a level of evidence to each article. For a full description of these Evidence-Based Medicine ratings, please refer to the Table of Contents or the online Instructions to Authors www.springer.com/00266 .
Indexed as
Identifiers
41345305What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.