Evidence map›Paper›PMID 41345271›Full record

ArticleCommunications medicine2025

Health outcomes in hospitalised and non-hospitalised individuals after COVID-19, an observational, cross-sectional study.

Malin Nygren-Bonnier, Anna Svensson-Raskh, Linda Holmström, Anna Törnberg, Annie Svensson, Daniel Loewenstein, Malin Regardt, Mikael Björnson, Carl Hallberg, Mike Kemani and 21 more

Abstract read
In one paragraph

Article in Communications medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Trial
  2. Observational
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

31 authors.

Malin Nygren-BonnierDepartment of Neurobiology, Care Sciences and Society, Division of Physiotherapy, Karolinska Institutet, Stockholm, Sweden. malin.nygren-bonnier@ki.se.ORCID http://orcid.org/0000-0001-6731-8468
Anna Svensson-RaskhDepartment of Neurobiology, Care Sciences and Society, Division of Physiotherapy, Karolinska Institutet, Stockholm, Sweden.
Linda HolmströmWomen's Health, and Allied Health Professionals Theme, Medical Unit Allied Health Professionals, Karolinska University Hospital, Stockholm, Sweden.
Anna TörnbergDepartment of Neurobiology, Care Sciences and Society, Division of Physiotherapy, Karolinska Institutet, Stockholm, Sweden.ORCID http://orcid.org/0009-0008-8320-9948
Annie SvenssonDepartment of Neurobiology, Care Sciences and Society, Division of Physiotherapy, Karolinska Institutet, Stockholm, Sweden.
Daniel LoewensteinDepartment of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.ORCID http://orcid.org/0000-0003-2118-3056
Malin RegardtWomen's Health, and Allied Health Professionals Theme, Medical Unit Allied Health Professionals, Karolinska University Hospital, Stockholm, Sweden.
Mikael BjörnsonDepartment of Medicine Solna, Division of Infectious Diseases, Karolinska Institutet, Stockholm, Sweden.
Carl HallbergDepartment of Neurobiology, Care Sciences and Society, Division of Physiotherapy, Karolinska Institutet, Stockholm, Sweden.
Mike KemaniWomen's Health, and Allied Health Professionals Theme, Medical Unit Allied Health Professionals, Karolinska University Hospital, Stockholm, Sweden.
Anita Mc AllisterDepartment of Clinical Science, Intervention and Technology, Division of Speech and language Pathology, Karolinska Institutet, Stockholm, Sweden.
Joakim Körner GustafssonWomen's Health, and Allied Health Professionals Theme, Medical Unit Allied Health Professionals, Karolinska University Hospital, Stockholm, Sweden.
Alexandra HalvarssonDepartment of Neurobiology, Care Sciences and Society, Division of Physiotherapy, Karolinska Institutet, Stockholm, Sweden.
Urban EkmanWomen's Health, and Allied Health Professionals Theme, Medical Unit Allied Health Professionals, Karolinska University Hospital, Stockholm, Sweden.
Linda NordstrandWomen's Health, and Allied Health Professionals Theme, Medical Unit Allied Health Professionals, Karolinska University Hospital, Stockholm, Sweden.
Susanne GuidettiWomen's Health, and Allied Health Professionals Theme, Medical Unit Allied Health Professionals, Karolinska University Hospital, Stockholm, Sweden.ORCID http://orcid.org/0000-0001-6878-6394
Lena AnmyrWomen's Health, and Allied Health Professionals Theme, Medical Unit Allied Health Professionals, Karolinska University Hospital, Stockholm, Sweden.
Maria BragesjöDepartment of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet, & Stockholm Health Care Services, Region Stockholm, Stockholm, Sweden.
Jenny Åström ReitanWomen's Health, and Allied Health Professionals Theme, Medical Unit Allied Health Professionals, Karolinska University Hospital, Stockholm, Sweden.ORCID http://orcid.org/0000-0002-0307-3673
Farzaneh BadinlouDepartment of Clinical Neuroscience, Centre for Psychiatry Research, Karolinska Institutet, & Stockholm Health Care Services, Region Stockholm, Stockholm, Sweden.
Oili DahlDepartment of Neurobiology, Care sciences and Society, Division of Nursing, Karolinska Institutet, Stockholm, Sweden.
Eva ÅkermanDepartment of Neurobiology, Care sciences and Society, Division of Nursing, Karolinska Institutet, Stockholm, Sweden.
Pär VillnerDivision of Biostatistics Institute of Environmental Medicine, Karolinska Institutet, Stockholm, Sweden.
Petter BrodinDepartment of Women´s and Children´s Health, Karolinska Institutet, Stockholm, Sweden.
Kenneth CaidahlDepartment of Molecular Medicine and Surgery, Karolinska Institutet, Stockholm, Sweden.ORCID http://orcid.org/0000-0002-5079-9696
Marcus StåhlbergDepartment of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden.
Artur FedorowskiDepartment of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden.ORCID http://orcid.org/0000-0002-5352-6327
Magnus SköldDepartment of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden.
Michael RunoldDepartment of Medicine, Solna, Karolinska Institutet, Stockholm, Sweden.
Judith Bruchfeld *Department of Medicine Solna, Division of Infectious Diseases, Karolinska Institutet, Stockholm, Sweden.ORCID http://orcid.org/0000-0001-5399-0982
Elisabeth Rydwik *Department of Neurobiology, Care Sciences and Society, Division of Physiotherapy, Karolinska Institutet, Stockholm, Sweden.

Funding

Hjärt-Lungfonden (Swedish Heart-Lung Foundation) 2021-0024, 2021-0539, 2022-0563, 2021-0029, 2022-0224, 2020-0637, 2021-0536Svenska Forskningsrådet Formas (Swedish Research Council Formas) 2020-02789Vetenskapsrådet (Swedish Research Council) 2021-02844, 2022-00837
6 · The paper itself

Abstract

backgroundBoth hospitalised (H) and non-hospitalised (NH) individuals may have different symptoms and impairments after COVID-19. We aimed to explore symptoms, mental and physical health after initial COVID-19 for both groups of individuals and the association between physical and mental impairments in relation to self-rated health status and to identify different cluster profiles.

methodsParticipants were recruited between June 2020 until December 2022 at the Karolinska University Hospital, Sweden. Data was collected at first assessment after COVID-19 and consisted of demographics, medical history, symptoms and results from physical function tests and self-reported questionnaires.

resultsHere we show that among 931 participants, the H-group are older (mean age 56.7 years) and predominantly male (72%), while the NH-group are younger (mean age 44.4 years) and mostly female (84%). Fatigue, dyspnoea, joint pain, paraesthesia, and chest pressure are common symptoms reported across all participants. Physical function is lower than predicted in both groups and the NH-group have higher prevalence of depression and fatigue. These impairments together with dyspnoea, number of symptoms and sick leave are also associated with reduced self-rated health. Four specific cluster profiles have been identified, and 66.4% of the participants have severe to moderate impairments.

conclusionsRegardless of the initial level of care approximately two-thirds of the participants exhibit various physical and mental impairments associated to self-rated health after COVID-19. We propose that defining specific cluster profiles is crucial for tailoring management of post-COVID sequelae. Further long-term studies are needed to understand recovery trajectories to optimise targeted interventions.

Identifiers

PMID41345271
PMCPMC12678783

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.