Evidence map›Paper›PMID 41345235›Full record

ArticleScientific reports2025

Artificial intelligence-assisted prediction of Demodex mite density in facial erythema.

Jemin Kim, Yun Na Lee, Jihee Boo, Inrok Oh, Changyoon Lee, Joo Hee Lee, Ye Seul Choi, Hyun Kim, Jung Im Na, Jihee Kim and 1 more

Abstract read
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. NN-assisted image analysis for quantifying intracellularFrontiers in cellular and infection microbiology · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Jemin Kim *Department of Dermatology, Yongin Severance Hospital Yonsei University College of Medicine, Gyeonggi-do 16995, Yongin-si, Korea.
Yun Na Lee *Department of Transdisciplinary Medicine , Seoul National University Hospital , Seoul, 03080, Korea.
Jihee BooDepartment of Dermatology, Yongin Severance Hospital Yonsei University College of Medicine, Gyeonggi-do 16995, Yongin-si, Korea.
Inrok OhLG Chem Ltd , Seoul, Korea.
Changyoon LeeDepartment of Medicine , Yonsei University College of Medicine , Seoul, 03722, Korea.
Joo Hee LeeDepartment of Dermatology and Cutaneous Biology Research Institute , Severance Hospital Yonsei University College of Medicine , Seoul, 03722, Korea.
Ye Seul ChoiDepartment of Dermatology, Yongin Severance Hospital Yonsei University College of Medicine, Gyeonggi-do 16995, Yongin-si, Korea.
Hyun KimDepartment of Dermatology, Yongin Severance Hospital Yonsei University College of Medicine, Gyeonggi-do 16995, Yongin-si, Korea.
Jung Im NaDepartment of Dermatology, Seoul National University Bundang Hospital, Gyeonggi-do 13620, Seongnam-si, Korea.
Jihee KimDepartment of Dermatology, Yongin Severance Hospital Yonsei University College of Medicine, Gyeonggi-do 16995, Yongin-si, Korea. mygirljihee@yuhs.ac.
Chang Ook ParkDepartment of Dermatology and Cutaneous Biology Research Institute , Severance Hospital Yonsei University College of Medicine , Seoul, 03722, Korea. COPARK@yuhs.ac.

Funding

Ministry of Health and Welfare HI14C1324National Institutes of Health, South Korea RS-2023-00265913National Research Foundation of Korea RS-2023-00234581National Research Foundation of Korea RS-2025-16070039Yonsei University College of Medicine 6-2023-0098Yonsei University College of Medicine 6-2024-0056
6 · The paper itself

Abstract

Current detection methods of Demodex mite density in facial erythema are semi-invasive or operator-dependent. We developed and evaluated a deep learning model (DemodexNet) for predicting Demodex mite density and assessed its impact on the diagnostic performance of dermatologists. This study included 1,124 patients with facial erythema who underwent Demodex mite density measurement at two referral hospitals between January 2016 and August 2023. DemodexNet achieved area under the receiver operating characteristic curve values of 0.823-0.865 in internal testing, with lower values observed in the external testing set. AI-assisted evaluation was associated with an increase in diagnostic accuracy among dermatologists from 63.7% to 70.6% (P < .001). Less experienced dermatologists and those with higher trust in AI showed greater performance gains. The model recognized central facial regions and individual lesions characteristic of demodicosis. DemodexNet demonstrates promising performance in predicting Demodex mite density and significantly improves dermatologists' diagnostic accuracy. As this proof-of-concept study was limited to Korean patients with Fitzpatrick skin types III-IV, validation in diverse populations is required before broader clinical application.

Indexed as

Artificial IntelligenceErythemaFaceMite InfestationsMitesAdultAgedAnimalsDeep LearningFemaleHumansMaleMiddle AgedROC CurveArtificial intelligenceDeep learningDemodex mitesFacial erythemaRosacea

Identifiers

PMID41345235
PMCPMC12775504

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.