Evidence map›Paper›PMID 41345122›Full record

ReviewNature communications2025

Reversibility, regulation, and the community of development: the legacy of Sir John B. Gurdon.

Richard P Halley-Stott, Eva Hörmanseder, Jerome Jullien, Vincent Pasque

Abstract readHistorical ArticleReview
In one paragraph

Review in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Richard P Halley-StottDepartment of Radiation Oncology, Groote Schuur Hospital and University of Cape Town, Cape Town, South Africa.
Eva HörmansederResearch Institute of Molecular Pathology (IMP), Vienna BioCenter, Vienna, Austria. eva.hoermanseder@imp.ac.at.ORCID http://orcid.org/0000-0003-0340-6340
Jerome JullienNantes Université, CHU Nantes, INSERM, Center for Research in Transplantation and Translational Immunology, Nantes, France.
Vincent PasqueKU Leuven, Leuven Institute for Single Cell Omics (LISCO), Department of Development and Regeneration, Leuven, Belgium.ORCID http://orcid.org/0000-0002-5129-0146

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

John B. Gurdon approached biology with characteristic clarity and patience, asking not only what happens in development, but how much of a molecule is present, and for how long. His nuclear-transfer experiments revealed that cellular identity is not fixed but can be reset, reshaping both biology and medicine. Through studies of oocytes, translational control, and the community effect, he showed that stability in living systems arises from persistence and interaction. His influence reached far beyond the bench: through generosity and curiosity, he nurtured a community of scientists who, like their mentor, enjoy asking how a cell knows what to be.

Indexed as

Developmental BiologyAnimalsHistory, 20th CenturyHistory, 21st CenturyHumansNuclear Transfer TechniquesOocytes

Identifiers

PMID41345122
PMCPMC12678784

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.