Evidence map›Paper›PMID 41345089›Full record

ReviewNature communications2025

Considerations and perspectives on phage therapy from the transatlantic taskforce on antimicrobial resistance.

Kyung Moon, Carmen Coxon, Christine Årdal, Radu Botgros, Sarah Djebara, Laura Durno, Cara R Fiore, Jean-Baptiste Perrin, Dennis M Dixon, Marco Cavaleri

Abstract readReview
In one paragraph

Review in Nature communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
  4. UropathogenicAntibiotics (Basel, Switzerland) · 2026
    Review
  5. Article
  6. Review
  7. From screening to treatment:Microbiology spectrum · 2026
    Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Review
  13. Review
  14. Lipopolysaccharide-targeting treatments for multidrug-resistantExpert opinion on therapeutic targets · 2026
    Review
  15. Review
  16. Phage-Based Approaches to ChronicAntibiotics (Basel, Switzerland) · 2026
    Review
  17. Article
  18. Review
  19. Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Kyung MoonNational Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA. kyung.moon@nih.gov.ORCID http://orcid.org/0000-0001-5809-1601
Carmen CoxonMHRA Science Campus, Blanche Lane, South Mimms, Hertfordshire, UK. Carmen.Coxon@mhra.gov.uk.
Christine ÅrdalNorwegian Institute of Public Health, Oslo, Norway.ORCID http://orcid.org/0000-0002-0891-0549
Radu BotgrosPublic Health Threats Department, European Medicines Agency, Amsterdam, the Netherlands.
Sarah DjebaraCenter for Infectious diseases ID4C, Queen Astrid military hospital, Brussels, Belgium.
Laura DurnoHealth Products and Food Branch, Health Canada, Ottawa, Canada.
Cara R FioreCenter for Biologics Evaluation and Research, the U S Food and Drug Administration (US FDA), Silver Spring, MD, USA.
Jean-Baptiste PerrinEuropean Commission, Health emergency preparedness and response authority (HERA), Brussels, Belgium. Jean-Baptiste.PERRIN@ec.europa.eu.
Dennis M DixonNational Institute of Allergy and Infectious Diseases, National Institutes of Health, Bethesda, MD, USA.
Marco CavaleriPublic Health Threats Department, European Medicines Agency, Amsterdam, the Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Amid rising antimicrobial resistance and limited antibiotic innovation, bacteriophages are gaining attention as potential therapeutics across human health, animal, and food sectors. Despite historical use, their clinical application in humans remains constrained by scientific, industrial, and regulatory challenges. To address these issues, the Transatlantic Task Force on Antimicrobial Resistance (TATFAR) convened sessions with experts from member parties. This perspective synthesizes insights from the TATFAR group, highlighting regulatory differences, research gaps, and opportunities for international collaborations to advance bacteriophage therapy.

Indexed as

Bacterial InfectionsBacteriophagesDrug Resistance, BacterialPhage TherapyAdvisory CommitteesAnimalsAnti-Bacterial AgentsHumansAnti-Bacterial Agents

Identifiers

PMID41345089
PMCPMC12678583

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.