Evidence map›Paper›PMID 41344697›Full record

ArticleAddiction (Abingdon, England)2026

Associations between county-level e-cigarette-inclusive Tobacco 21 law population coverage and e-cigarette use behaviors among United States adolescents in Monitoring the Future.

James H Buszkiewicz, Catherine A Vander Woude, Yanmei Xie, Steven Cook, Bukola Usidame Peters, Megan E Patrick, Michael R Elliott, James F Thrasher, Nancy L Fleischer

Abstract read
In one paragraph

Article in Addiction (Abingdon, England), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

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5 · Who and what money

Authors and funding

9 authors.

James H BuszkiewiczDepartment of Epidemiology, University of Michigan, Ann Arbor, MI, USA.ORCID https://orcid.org/0000-0002-7919-7103
Catherine A Vander WoudeDepartment of Epidemiology, University of Michigan, Ann Arbor, MI, USA.ORCID https://orcid.org/0009-0006-9223-8623
Yanmei XieDepartment of Epidemiology, University of Michigan, Ann Arbor, MI, USA.
Steven CookDepartment of Epidemiology, University of Michigan, Ann Arbor, MI, USA.ORCID https://orcid.org/0000-0002-6363-2940
Bukola Usidame PetersDepartment of Public Health, Purdue University, West Lafayette, IN, USA.ORCID https://orcid.org/0000-0002-9716-0670
Megan E PatrickSurvey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA.ORCID https://orcid.org/0000-0003-3594-4944
Michael R ElliottSurvey Research Center, Institute for Social Research, University of Michigan, Ann Arbor, MI, USA.
James F ThrasherDepartment of Health Promotion, Education, and Behavior, Arnold School of Public Health, University of South Carolina, Columbia, SC, USA.ORCID https://orcid.org/0000-0001-6418-4863
Nancy L FleischerDepartment of Epidemiology, University of Michigan, Ann Arbor, MI, USA.ORCID https://orcid.org/0000-0002-4371-9133

Funding

Monitoring the Future: Drug Use & Lifestyles of American Youth (Supp1: Nicotine Pouch and E-cigarette Use Among US Adolescents: National Estimates of Brand Use and Flavor Preferences)R01DA001411 · NIDA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Richard A Miech · 1985 to 2026
$144.9M
Research Education CoreP30AG024824 · NIA · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Lona Mody, RAYMOND L YUNG · 2004 to 2026
$29.2M
The Impact of Tobacco Control Policies on Health Equity in the United States - MERIT ExtensionR37CA214787 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI FLEISCHER, NANCY · 2018 to 2024
$4.2M
Interdisciplinary Research Training Center in Cancer Care DeliveryT32CA236621 · NCI · UNIVERSITY OF MICHIGAN AT ANN ARBOR · PI Lauren P Wallner · 2020 to 2026
$2.8M
NCI NIH HHS R37CA21478NCI NIH HHS R37 CA214787NCI NIH HHS T32 CA236621NIA NIH HHS P30 AG024824NIDA NIH HHS R01 DA001411NIDA NIH HHS R01DA001411
6 · The paper itself

Abstract

BACKGROUND AND

aimsIn the United States (US), Tobacco 21 (T21) laws set the minimum legal sale age for all tobacco products to 21 years. This study aimed to examine whether e-cigarette-inclusive T21 laws were associated with e-cigarette use behaviors and related disparities among US adolescents.

designWe used nationally representative, repeated cross-sectional Monitoring the Future data to compare self-reported current e-cigarette use (2014-2022) and first e-cigarette initiation (2015-2022) among adolescents in counties with 100% ('full') versus <100% ('partial or no') e-cigarette-inclusive T21 law population coverage using modified Poisson regression, examining differences by sex, race and ethnicity, parental educational attainment and college educational expectations through interactions.

settingUnited States.

participants8th, 10th and 12th graders. MEASUREMENTS: County-level e-cigarette-inclusive T21 law population coverage was determined using Tobacco 21 Population Coverage Database and US Census Bureau population data. Current e-cigarette use was defined as any past 30-day use among the entire sample. First e-cigarette initiation was defined as first use in the current grade among adolescents who had not initiated use prior to the current grade.

findingsCompared with 8th, 10th and 12th graders in counties with partial or no e-cigarette-inclusive T21 law coverage, 8th [marginal effect (ME) = -1.8%, 95% confidence interval (CI) = -3.1% to -0.6%], 10th (ME = -2.6%, 95% CI = -4.6% to -0.6%) and 12th graders (ME = -2.7%, 95% CI = -5.2% to -0.1%) in counties with full coverage had a lower current e-cigarette use prevalence. For current e-cigarette use, we also observed statistically significant interactions by sociodemographic factors. Across all grades, full [8th: predicted prevalence (PP) = 5.9%, 95% CI = 4.7%-7.1%; 10th: PP = 11.8%, 95% CI = 10.2%-13.4%; 12th: 18.1%, 95% CI = 15.6%-20.6%] versus partial or no coverage (8th: PP = 7.5%, 95% CI = 6.2%-8.8%; 10th: PP = 16.3%, 95% CI = 15.0%-17.6%; 12th: 23.4%, 95% CI = 21.9%-24.8%) was associated with lower current e-cigarette use among males but not females. By race and ethnicity, associations were statistically significant across all grades, but the magnitude and direction of these associations varied by subgroup and grade. Among 12th graders, full (PP = 16.1%, 95% CI = 13.9%-18.3%) versus partial or no coverage (PP = 20.5%, 95% CI = 19.0%-22.1%) was associated with lower current e-cigarette use among those who said they 'probably will' graduate from a four-year college but not among those with other educational expectations. We did not find sufficient evidence to support an association between e-cigarette-inclusive T21 law coverage and first e-cigarette initiation overall or across sociodemographic subgroups.

conclusionsE-cigarette-inclusive Tobacco 21 laws appear to be associated with lower current e-cigarette use among US adolescents. However, we lacked sufficient evidence to support an association with first e-cigarette use initiation. We also observed sociodemographic differences in these associations for current e-cigarette use.

Indexed as

Adolescent BehaviorElectronic Nicotine Delivery SystemsTobacco ProductsVapingAdolescentCommerceCross-Sectional StudiesFemaleHumansMaleUnited StatesYoung Adultadolescentse‐cigarettesENDShealth disparitiestobacco 21 lawstobacco youth access

Identifiers

PMID41344697
PMCPMC12710897

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.