Evidence map›Paper›PMID 41344600›Full record

ArticleACS applied materials & interfaces2025

Ultrasmall Gold Nanoparticles as "Three-in-One" Enzyme-Mimicking Nanocatalysts for Combined Sonodynamic/Catalytic Therapy in Breast Cancer.

Adilet Beishenaliev, Yean Leng Loke, Chung-Yin Lin, Sook Jing Goh, Jaya Seema, Yuhan Huang, Xin Yun Lim, Yu-Wen Chen, Bey Fen Leo, Chia-Yu Chang and 5 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in ACS applied materials & interfaces, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors.

Adilet BeishenalievDepartment of Pharmacology, Faculty of Medicine, Universiti Malaya, 50603 Kuala Lumpur, Malaysia.ORCID 0000-0001-8555-910X
Yean Leng LokeDepartment of Chemistry, Faculty of Science, Universiti Malaya, 50603 Kuala Lumpur, Malaysia.
Chung-Yin LinResearch Center for Radiation Medicine, Chang Gung University, 333 Taoyuan, Taiwan.
Sook Jing GohDepartment of Pharmacology, Faculty of Medicine, Universiti Malaya, 50603 Kuala Lumpur, Malaysia.
Jaya SeemaInstitute of Biomedical Sciences, Academia Sinica, 11529 Taipei, Taiwan.
Yuhan HuangInstitute of Biomedical Sciences, Academia Sinica, 11529 Taipei, Taiwan.
Xin Yun LimDepartment of Pharmacology, Faculty of Medicine, Universiti Malaya, 50603 Kuala Lumpur, Malaysia.
Yu-Wen ChenBiomedical Translation Research Center, Academia Sinica, 11529 Taipei, Taiwan.
Bey Fen LeoDepartment of Molecular Medicine, Faculty of Medicine, Universiti Malaya, 50603 Kuala Lumpur, Malaysia.ORCID 0000-0002-8075-0295
Chia-Yu ChangDepartment of Biological Science and Technology, College of Engineering Bioscience, National Yang Ming Chiao Tung University, 30068 Hsinchu, Taiwan.
Lip Yong ChungDepartment of Pharmaceutical Chemistry, Faculty of Pharmacy, Universiti Malaya, 50603 Kuala Lumpur, Malaysia.ORCID 0000-0002-3596-768X
Chia-Ching ChangDepartment of Biological Science and Technology, College of Engineering Bioscience, National Yang Ming Chiao Tung University, 30068 Hsinchu, Taiwan.ORCID 0000-0002-3444-0894
Yin Yin TeoDepartment of Chemistry, Faculty of Science, Universiti Malaya, 50603 Kuala Lumpur, Malaysia.ORCID 0000-0002-2755-5589
Dennis W HwangInstitute of Biomedical Sciences, Academia Sinica, 11529 Taipei, Taiwan.ORCID 0000-0001-9974-4728
Lik Voon KiewDepartment of Pharmacology, Faculty of Medicine, Universiti Malaya, 50603 Kuala Lumpur, Malaysia.ORCID 0000-0002-6855-9631

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The combination of catalytic therapy and sonodynamic therapy (SDT) emerges as a promising approach for the treatment of solid tumors. Smartly designed nanocatalysts can activate tumor-localized catalytic reactions to convert hydrogen peroxide (H

Indexed as

Antineoplastic AgentsBreast NeoplasmsGoldMetal NanoparticlesUltrasonic TherapyAnimalsCatalysisCell Line, TumorFemaleHumansHydrogen PeroxideHydroxyl RadicalMiceMice, Inbred BALB CAntineoplastic AgentsGoldHydrogen PeroxideHydroxyl Radicalcatalytic therapynanocatalystsonodynamic therapysonosensitizerultrasmall gold nanoparticlesultrasound

Identifiers

PMID41344600
PMCPMC12723636

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.