Evidence map›Paper›PMID 41344093›Full record

ArticlePoultry science2026

Clonal dissemination of ST19 Salmonella Typhimurium within a Chinese poultry breeding pyramid and One-Health implications.

Jie Zhang, Wei Xu, Ke Wu, Jian Yang, Changwei Lei, Anyun Zhang, Xin Yang, Hongning Wang

Abstract read
In one paragraph

Article in Poultry science, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Jie ZhangKey Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610000, China; Animal Disease Prevention and Green Development Key Laboratory of Sichuan Province, Chengdu 610000, China.
Wei XuKey Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610000, China; Animal Disease Prevention and Green Development Key Laboratory of Sichuan Province, Chengdu 610000, China.
Ke WuKey Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610000, China; Animal Disease Prevention and Green Development Key Laboratory of Sichuan Province, Chengdu 610000, China.
Jian YangKey Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610000, China; Animal Disease Prevention and Green Development Key Laboratory of Sichuan Province, Chengdu 610000, China.
Changwei LeiKey Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610000, China; Animal Disease Prevention and Green Development Key Laboratory of Sichuan Province, Chengdu 610000, China.
Anyun ZhangKey Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610000, China; Animal Disease Prevention and Green Development Key Laboratory of Sichuan Province, Chengdu 610000, China.
Xin YangKey Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610000, China; Animal Disease Prevention and Green Development Key Laboratory of Sichuan Province, Chengdu 610000, China.
Hongning WangKey Laboratory of Bio-Resource and Eco-Environment of Ministry of Education, College of Life Sciences, Sichuan University, Chengdu 610000, China; Animal Disease Prevention and Green Development Key Laboratory of Sichuan Province, Chengdu 610000, China. Electronic address: whongning@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Salmonella poses a major threat to global poultry production and food safety. However, the transmission dynamics of Salmonella within poultry breeding hierarchies and their implications for the One Health remain poorly understood. This study bridges this knowledge gap by conducting epidemiological surveillance and genomic analysis of ST19 S. Typhimurium across a poultry breeding chain in China, augmented by comparative genomics of publicly available strains from diverse ecological sources. From 1,047 samples collected in a breeding system in Fujian Province, we recovered 37 ST19 S. Typhimurium isolates. Genomic comparison showed high clonality (≤2 SNPs) across them, revealing clonal dissemination of ST19 S. Typhimurium within flocks in the poultry breeding pyramid. Evolutionary analysis with 845 public Chinese ST19 S. Typhimurium genomes revealed close genetic links between the clone from this study and human clinical strains across multiple regions in China, providing evidence of cross-species transmission between poultry and humans. Furthermore, comparative genomic analysis elucidated the significant role of IncHI2 plasmids in facilitating the dissemination of antimicrobial resistance (AMR). In conclusion, this study underscores the clonal spread of ST19 S. Typhimurium within the poultry breeding pyramid and highlights potential One-Health risks, providing a scientific reference for designing targeted interventions to mitigate Salmonella transmission across poultry production systems and human populations.

Indexed as

ChickensOne HealthPoultry DiseasesSalmonella Infections, AnimalSalmonella typhimuriumAnimalsBreedingChinaClonal transmissionOne HealthPoultry breeding systemST19 Salmonella Typhimurium

Identifiers

PMID41344093
PMCPMC12719724

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.