ArticlePloS one2025
Establishment and culture of mouse oviductal organoids and isolation and characterization of their secreted extracellular vesicles.
Article in PloS one, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
Abstract
Oviductal (fallopian tube) cell cultures are widely used to improve understanding of oviductal pathophysiology and to improve sperm and embryo quality via co-culture. One type of oviductal cell culture is organoids, a three-dimensional cell culture that can mimic the oviduct in vitro long-term (months). Because organoids maintain their structure and function similar to in vivo, their secretions tend to be more similar to in vivo cellular products. One of these organoid secretions includes extracellular vesicles (EVs), which are bioactive nanoparticles secreted by cells for intercellular communication. Here we report a protocol for isolation of mouse oviducts, establishment and long-term culture of mouse oviductal organoids, and isolation and characterization of the EVs secreted by mouse oviductal organoids. This lab protocol can be used for research of oviductal physiology and pathology and improvement of assisted reproductive technologies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.