Evidence map›Paper›PMID 41343073›Full record

Trial reportEuropean journal of applied physiology2026

Intelligent circuit exercise training improves platelet mitochondrial bioenergetic efficiency in sedentary men.

Ai Yin Lim, Chi-Yao Chiang, Yu-Ting Lin, Chih-Chin Hsu, Jong-Shyan Wang

Registry-linked trialAbstract readRandomized Controlled Trial
PubMed Publisher
In one paragraph

Trial report in European journal of applied physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT07790263 (Intelligent Precision Exercise Integrated Health Management), which is not on this map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT07790263 nacompletednot on this map

Intelligent Precision Exercise Integrated Health Management: Construction of Innovative Technology and Management Models and Clinical Evidence Research in Elderly Communities.

TypeinterventionalSponsorChang Gung Memorial HospitalRan2024 to 2026Enrolled256ConditionsAging, Autonomic Nervous System, HemodynamicsArmsSmart Circuit Exercise Program
3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Ai Yin LimHealthy Aging Research Center, Graduate Institute of Rehabilitation Sciences, Chang Gung University, 259 Wen-Hwa 1St Road, Kwei-Shan, Taoyuan, 333, Taiwan.
Chi-Yao ChiangHealthy Aging Research Center, Graduate Institute of Rehabilitation Sciences, Chang Gung University, 259 Wen-Hwa 1St Road, Kwei-Shan, Taoyuan, 333, Taiwan.
Yu-Ting LinHealthy Aging Research Center, Graduate Institute of Rehabilitation Sciences, Chang Gung University, 259 Wen-Hwa 1St Road, Kwei-Shan, Taoyuan, 333, Taiwan.
Chih-Chin HsuDepartment of Physical Medicine and Rehabilitation, Chang Gung Memorial Hospital, Keelung, Taiwan.
Jong-Shyan WangHealthy Aging Research Center, Graduate Institute of Rehabilitation Sciences, Chang Gung University, 259 Wen-Hwa 1St Road, Kwei-Shan, Taoyuan, 333, Taiwan. s5492@cgu.edu.tw.ORCID http://orcid.org/0000-0002-3095-9357

Funding

Chang Gung Memorial Hospital, Linkou CMRPD1L0211National Science and Technology Council NSTC 113-2314-B-182-051-MY3
6 · The paper itself

Abstract

purposePlatelet mitochondria modulate thrombogenesis, whereas regular exercise reduces vascular thrombotic risks. This study explores how the Intelligent circuit (CET) and single (SET) exercise regimens affect platelet mitochondrial bioenergetics in sedentary men.

methodsFifty healthy sedentary men were randomly assigned to participate in CET [n = 17, circuit exercise on bicycle, rowing, and elliptical ergometers at 60% heart rate reserve (HRR), 10 min of each exercise followed by 1 min of rest] or SET (n = 17, three sets of cycling at 60% HRR for 10 min followed by 1-min rest), or to a control group (CON, n = 17) that did not receive exercise intervention. Both CET and SET were conducted using real-time HR and workload feedback. Systemic aerobic fitness and capacities of mitochondrial electron transport system (ETS) and oxidative phosphorylation (OXPHOS) in platelets were measured through automatic gas analysis and high-resolution respirometry, respectively.

resultsBoth CET and SET significantly improved VO

conclusionBoth CET and SET improve systemic aerobic capacity and simultaneously increase platelet FADH2-dependent OXPHOS and ETS capacities in sedentary males. Moreover, changes in systemic aerobic capacity are associated with changes in platelet mitochondrial bioenergetics following the Intelligent exercise regimens.

Indexed as

Blood PlateletsEnergy MetabolismExerciseMitochondriaAdultHumansMaleOxidative PhosphorylationOxygen ConsumptionSedentary BehaviorYoung AdultAerobic capacityIntelligent exerciseMitochondriaPlatelet

Identifiers

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.