Evidence map›Paper›PMID 41343066›Full record

ArticleEuropean journal of applied physiology2026

Endurance training induces asymmetric brain oxygenation adaptations in the left and right prefrontal cortex during submaximal exercise.

Ioannis Loukas, Maria Koskolou, Gregory Bogdanis, Nickos Geladas

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Article in European journal of applied physiology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

4 authors.

Ioannis LoukasDivision of Sports Medicine and Biology of Exercise, School of Physical Education and Sport Science, National and Kapodistrian University of Athens, Ethnikis Antistasis 41, 17237, Daphne, Athens, Greece. iloukas@phed.uoa.gr.ORCID http://orcid.org/0009-0002-8139-3389
Maria KoskolouDivision of Sports Medicine and Biology of Exercise, School of Physical Education and Sport Science, National and Kapodistrian University of Athens, Ethnikis Antistasis 41, 17237, Daphne, Athens, Greece.
Gregory BogdanisAthletics Laboratory, School of Physical Education and Sport Science, National and Kapodistrian University of Athens, 17237, Daphne, Greece.
Nickos GeladasDivision of Sports Medicine and Biology of Exercise, School of Physical Education and Sport Science, National and Kapodistrian University of Athens, Ethnikis Antistasis 41, 17237, Daphne, Athens, Greece.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeSufficient blood and oxygen supply to the brain is crucial for optimal performance. This study examined the effects of endurance training on oxygen delivery to the right and left prefrontal cortex.

methodsSixteen male distance runners (age: 34.1 ± 5.1 yrs, weight: 70.8 ± 4.1 kg) trained five times per week for eight weeks. Training included two high-intensity interval sessions (90-100% VO

resultsVO

conclusionsEndurance training facilitate redistribution of blood volume from the muscle to the brain enhancing oxygen delivery. The right and left prefrontal cortex appear to adapt differently to endurance training, suggesting distinct functions in regulating aerobic exercise tolerance.

Indexed as

Adaptation, PhysiologicalEndurance TrainingExerciseOxygenOxygen ConsumptionPhysical EndurancePrefrontal CortexAdultHemoglobinsHumansMaleMuscle, SkeletalOxyhemoglobinsRunningdeoxyhemoglobinHemoglobinsOxygenOxyhemoglobinsAerobic adaptationsBlood volume redistributionCentral nervous system and exercise

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.