ArticleMagma (New York, N.Y.)2026
Exercise MRI stress testing of the human heart at 3 Tesla: measurement precision of biventricular function and aortic blood flow during steady-state bicycling exercise.
Article in Magma (New York, N.Y.), 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
objectiveThis work aimed to demonstrate the feasibility of quantifying heart function during bicycling exercise with dynamic real-time cine MRI at 3 Tesla, and to assess its measurement precision. MATERIALS AND
methodsTwelve volunteers performed steady-state bicycling exercise, while real-time cine MR images were collected using a 72-channel receiver coil array and a parallel imaging acceleration factor of 5. Biventricular end-diastolic and end-systolic (ESV) volumes and function during exercise were compared with resting-state real-time cine MRI and conventional cardiac-gated cine MRI under breath holding, and validated against 2D phase-contrast MRI-based estimates of aortic blood flow. Precision was evaluated as the inter-session measurement repeatability.
resultsLeft (LV) and right ventricular (RV) stroke volumes (SV) increased progressively with exercise intensity, which was mediated by a decrease in ESV. Likewise, LV SV estimated with 2D phase-contrast MRI increased from 90 ± 17 mL at rest to 114 ± 29 mL during vigorous-intensity exercise. Repeatability coefficients were 52% and 41% for LV SV at moderate- and vigorous-intensity exercise, while RV SV repeatability coefficients were 58% and 42%, respectively. DISCUSSION: We established an exercise MRI stress testing protocol for quantifying biventricular volumes and function during moderate- and vigorous-intensity steady-state bicycling exercise.
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