Evidence map›Paper›PMID 41342932›Full record

ArticleJournal of anesthesia2026

Obstetric and anesthetic management of parturients with intracranial neurovascular abnormalities.

David Cho, Amanda L Johnson, Jeffrey J Pasternak, Tasha L Welch, Emily E Sharpe

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Article in Journal of anesthesia, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

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2 · The registry

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3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

5 authors.

David ChoMayo Clinic Alix School of Medicine, Rochester, MN, USA.
Amanda L JohnsonDepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic, 200 1St Street S.W, Rochester, MN, 55905, USA.
Jeffrey J PasternakDepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic, 200 1St Street S.W, Rochester, MN, 55905, USA.
Tasha L WelchDepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic, 200 1St Street S.W, Rochester, MN, 55905, USA.
Emily E SharpeDepartment of Anesthesiology and Perioperative Medicine, Mayo Clinic, 200 1St Street S.W, Rochester, MN, 55905, USA. sharpe.emily@mayo.edu.ORCID http://orcid.org/0000-0003-4232-0718

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeNo definite recommendations exist for anesthetic and obstetric management of pregnant patients with intracranial neurovascular disorders during delivery. This case series describes the management of pregnant patients with intracranial vascular abnormalities during delivery.

methodsInformation was gathered from institutional databases to include pregnant patients evaluated by neurology or neurosurgery at a single institution between January 2000 and August 2025 for any central nervous system vascular abnormality. Patients were included if evaluation by neurology or neurosurgery occurred either before, during pregnancy, or up to six months post-partum.

resultsThe study cohort consisted of 26 patients having 31 deliveries. The most common lesions were cavernous malformation (n = 8) and cerebral arteriovenous malformation (n = 8). The remainder had aneurysm (n = 4), dural arteriovenous fistula (n = 2), moyamoya disease (n = 2), venous angioma (n = 1), and carotid dissection (n = 1). Twenty-one deliveries were vaginal and 10 were cesarean delivery (CD). The presence of a neurovascular abnormality was an indication for induction of labor in three individuals and for CD in four deliveries. Neuraxial labor analgesia was used in 14 of the 21 patients who had vaginal delivery. Parturients who underwent CD had spinal anesthesia (n = 8), preexisting labor epidural anesthesia (n = 1), and general anesthesia (n = 1). There were no complications attributed to neuraxial anesthesia.

conclusionsThe presence of central nervous system vascular abnormalities in pregnant patients is rare but poses unique challenges to obstetric and anesthetic management. Neuraxial anesthesia and analgesia can be offered to women with central nervous system vascular abnormalities without abnormal neurologic symptoms.

Indexed as

Anesthesia, ObstetricalDelivery, ObstetricIntracranial Arteriovenous MalformationsAdultAnesthesia, EpiduralAnesthesia, SpinalCesarean SectionCohort StudiesFemaleHumansNeuroanesthesiaPregnancyRetrospective StudiesAneurysmArteriovenous malformationNeuraxialPregnancyVascular malformation

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.