Evidence map›Paper›PMID 41342919›Full record

ArticleWorld journal of urology2025

Applied trigonometry in elucidating the mechanism of post-HoLEP urinary incontinence.

Omri Schwartztuch Gildor, Tomer Mendelson, Fernando Gomez Sancha, Thomas Rw Herrmann, Cesare Scoffone, Tevita Aho, Lukas Lusuardi, Felipe Carvalho Antunes de Figueiredo, Galit Aviram, Amihay Nevo and 2 more

Abstract read
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In one paragraph

Article in World journal of urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Observational
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

12 authors.

Omri Schwartztuch Gildor *Departments of Urology, Affiliated to the Faculty of Medical and Health Sciences, Tel-Aviv Sourasky Medical Center, Tel-Aviv University, 6 Weizman Street, 6423906, Tel-Aviv, Israel.
Tomer Mendelson *Departments of Urology, Affiliated to the Faculty of Medical and Health Sciences, Tel-Aviv Sourasky Medical Center, Tel-Aviv University, 6 Weizman Street, 6423906, Tel-Aviv, Israel.
Fernando Gomez SanchaDepartment of Urology and Robotic Surgery, ICUA-Clínica CEMTRO, Madrid, Spain.
Thomas Rw HerrmannDepartment of Urology, Spital Thurgau AG, Kantonsspital Frauenfeld, Pfaffenholzstrasse 4, CH 8501, Frauenfeld, Switzerland.
Cesare ScoffoneDepartment of Urology, Cottolengo Hospital, Turin, Italy.
Tevita AhoCambridge University Hospitals NHS Foundation Trust, Cambridge, UK.
Lukas LusuardiDepartment of Urology, University Hospital Salzburg, Paracelsus Medical University, Salzburg, Austria.
Felipe Carvalho Antunes de FigueiredoDepartment of Urology, Pompéia Hospital, Caxias Do Sul, Brazil.
Galit AviramDepartment of Radiology, Affiliated to the Faculty of Medical and Health Sciences, Tel-Aviv Sourasky Medical Center, Tel-Aviv University, 6423906, Tel-Aviv, Israel.
Amihay NevoDepartments of Urology, Affiliated to the Faculty of Medical and Health Sciences, Tel-Aviv Sourasky Medical Center, Tel-Aviv University, 6 Weizman Street, 6423906, Tel-Aviv, Israel.
Ofer YossepowitchDepartments of Urology, Affiliated to the Faculty of Medical and Health Sciences, Tel-Aviv Sourasky Medical Center, Tel-Aviv University, 6 Weizman Street, 6423906, Tel-Aviv, Israel.
Mario SoferDepartments of Urology, Affiliated to the Faculty of Medical and Health Sciences, Tel-Aviv Sourasky Medical Center, Tel-Aviv University, 6 Weizman Street, 6423906, Tel-Aviv, Israel. mariosofer@hotmail.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeStress urinary incontinence (SUI) after holmium laser enucleation of the prostate (HoLEP) is traditionally explained by longitudinal overstretching of the external urethral sphincter (EUS) during enucleation. We propose extreme radial forces exerted on the EUS as a novel mechanism for post-HoLEP SUI.

methodsWe assessed the resectoscope angles during enucleation as seen on external intraoperative pictures followed by fluoroscopically calibrated measurements and trigonometric calculations of EUS dilation as a function of the resectoscope angle and diameter and the membranous urethra length and width. Preoperative magnetic resonance imaging studies (n = 55) validated the trigonometric formula relative to SUI at one month post-HoLEP.

resultsThe maximal median angles for the non-SUI (n = 28) and SUI (n = 27) groups were 54° vs. 57° (p = 0.002), and the calculated sphincter dilations were 39mm vs. 49mm (p < 0.001), respectively. The sphincter dilation and resectoscope angle were the only independent predictors of SUI post-HoLEP in the univariate and multivariate regression models. A receiver-operating characteristic analysis found an area under the curve (AUC) of 0.849 for our formula, 0.764 for sphincter dilation, and 0.745 for the resectoscope angle. These AUCs were significantly better than those for prostate volume and patient age (p < 0.05).

conclusionsThe EUS dilation caused by radial forces exercised during resectoscope angulation is a plausible cause for post-HoLEP UI. It may also explain its temporality.

Indexed as

Lasers, Solid-StatePostoperative ComplicationsProstatectomyProstatic HyperplasiaUrethraUrinary Incontinence, StressAgedHumansMagnetic Resonance ImagingMaleMiddle AgedBPHHoLEPUrinary incontinence

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.