Evidence map›Paper›PMID 41342813›Full record

ArticleJACC. Case reports2026

Successful Transcatheter Tricuspid Valve Replacement 30 Years After Heart Transplantation.

Mateusz Orzalkiewicz, Tullio Palmerini, Elena Biagini, Chiara Marcelli, Maddalena Graziosi, Luciano Potena, Francesco Saia

Abstract readCase Reports
In one paragraph

Article in JACC. Case reports, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mateusz OrzalkiewiczInterventional Cardiology Unit, IRCCS University Hospital of Bologna, Policlinico S. Orsola, Bologna, Italy. Electronic address: matorzel@doctors.org.uk.
Tullio PalmeriniInterventional Cardiology Unit, IRCCS University Hospital of Bologna, Policlinico S. Orsola, Bologna, Italy.
Elena BiaginiCardiology Unit, IRCCS University Hospital of Bologna, Policlinico S. Orsola, Bologna, Italy; European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart-ERN GUARD-Heart, Bologna, Italy.
Chiara MarcelliHeart Failure and Transplant Unit, IRCCS University Hospital of Bologna, Policlinico S. Orsola, Bologna, Italy.
Maddalena GraziosiCardiology Unit, IRCCS University Hospital of Bologna, Policlinico S. Orsola, Bologna, Italy; European Reference Network for Rare, Low Prevalence and Complex Diseases of the Heart-ERN GUARD-Heart, Bologna, Italy.
Luciano PotenaHeart Failure and Transplant Unit, IRCCS University Hospital of Bologna, Policlinico S. Orsola, Bologna, Italy.
Francesco SaiaInterventional Cardiology Unit, IRCCS University Hospital of Bologna, Policlinico S. Orsola, Bologna, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTricuspid regurgitation (TR) is the most common valvular complication after orthotopic heart transplantation (HTx), but its management is challenging. CASE SUMMARY: A 70-year-old woman presented with severe symptomatic iatrogenic TR due to chordal rupture and flail septal leaflet 30 years after HTx. The heart team opted for transcatheter tricuspid valve replacement (TTVR), and a 44-mm Evoque valve (Edwards Lifesciences) was implanted without complications. The patient's symptoms improved, with reduced diuretic dose and echocardiography showing a well-functioning prosthesis. DISCUSSION: TTVR represents a novel therapy for patients with severe symptomatic TR. We present to our knowledge the first device success of TTVR in an HTx recipient, suggesting that TTVR is a viable option in these patients, who often present contraindications for redo cardiac surgery and transcatheter edge-to-edge repair. TAKE-HOME MESSAGES: Severe TR is a common complication after HTx, and high-risk surgery is rarely performed. Various transcatheter treatment options are available, but TTVR could become the treatment of choice pending more studies.

Indexed as

cardiac transplanttricuspid valvevalve replacement

Identifiers

PMID41342813
PMCPMC13100525

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.