Evidence map›Paper›PMID 41342660›Full record

ArticleStatistics in medicine2025

A Review of Methods for Research Synthesis.

Pär Villner, Matteo Bottai

Abstract read
In one paragraph

Article in Statistics in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. A Review of Methods for Research Synthesis.Statistics in medicine · 2025
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Pär VillnerDivision of Biostatistics, Karolinska Institutet, Stockholm, Sweden.ORCID https://orcid.org/0009-0005-0115-5455
Matteo BottaiDivision of Biostatistics, Karolinska Institutet, Stockholm, Sweden.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Meta-analysis consists of a wide range of methods for summarizing existing research, often by aggregating summary statistics. The dominant methods are the fixed effect and the random effects models, which assume that all studies included in a meta-analysis are similar. In many scenarios, the available studies differ in important ways, for example, in terms of research design and sample population. To handle this heterogeneity, more advanced methods are required. In this article, we review some of these methods that have been proposed in the past decades: hierarchical models, bias adjustment and quality weighting methods, Bayesian methods, and decision-centered meta-analysis. We aim to describe the theoretical rationale behind the methods and to give examples of applications. Each method has advantages and limitations, and we consider ways of combining methods.

Indexed as

Meta-Analysis as TopicBayes TheoremBiasHumansModels, StatisticalResearch Designdata heterogeneityeffect‐size surfacemeta‐analysisresearch synthesis

Identifiers

PMID41342660
PMCPMC12677128

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.