Evidence map›Paper›PMID 41342590›Full record

Observational studyEuropean journal of haematology2026

Safer Access With Fewer Transfusions: Revisiting Platelet Thresholds in Pediatric Central Venous Catheterization.

Alessandro Raffaele, Carlo Maria Ferlini, Marta Gazzaneo, Piero Giovanni Romano, Bilge Rol, Francesco Delle Cave, Stella Boghen, Tommaso Mina, Marco Zecca

Abstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in European journal of haematology, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Alessandro RaffaelePediatric Surgery Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.ORCID https://orcid.org/0000-0002-5146-1486
Carlo Maria FerliniPediatric Surgery Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.ORCID https://orcid.org/0009-0004-6265-5640
Marta GazzaneoPediatric Surgery Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.ORCID https://orcid.org/0000-0002-5666-8830
Piero Giovanni RomanoPediatric Surgery Unit, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.ORCID https://orcid.org/0000-0002-5036-0966
Bilge RolDepartment of Internal Medicine and Medical Therapy, University of Pavia, Pavia, Italy.ORCID https://orcid.org/0009-0003-6634-149X
Francesco Delle CavePediatric Hematology Oncology Department, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.ORCID https://orcid.org/0000-0002-3535-5333
Stella BoghenPediatric Hematology Oncology Department, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.ORCID https://orcid.org/0000-0003-2299-3536
Tommaso MinaPediatric Hematology Oncology Department, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.ORCID https://orcid.org/0000-0001-8829-6376
Marco ZeccaPediatric Hematology Oncology Department, Fondazione IRCCS Policlinico San Matteo, Pavia, Italy.ORCID https://orcid.org/0000-0002-8818-1744

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCentral venous catheters (CVCs) are essential in pediatric hematology-oncology, for the administration of chemotherapy and supportive therapy. Thrombocytopenia increases the risk of bleeding and current guidelines recommend prophylactic platelet transfusions below 40-50 × 10

methodsThis retrospective observational cohort study analyzed 274 pediatric patients undergoing CVC insertion (PICC, CICC, and FICC) at a tertiary center (2020-2023). Patients were stratified by platelet count using 50 × 10

resultsComplication rates did not differ significantly with platelets above or below 50 × 10

conclusionsA 30 × 10

Indexed as

Catheterization, Central VenousPlatelet TransfusionAdolescentCentral Venous CathetersChildChild, PreschoolFemaleHemorrhageHumansInfantMalePlatelet CountRetrospective StudiesThrombocytopeniacatheterizationcentral venous cathetershematologyoncologypatient care bundlespediatricsplatelet transfusionsimulation trainingthresholdthrombocytopenia

Identifiers

PMID41342590
PMCPMC13460834

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.