Evidence map›Paper›PMID 41342519›Full record

ArticleJournal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine2026

Liver Stiffness Characterization of OGT

Gilles Renault, Lenin Chinchilla, Lourdes Massengo, Pierre Monbernard, Fadila Benhamed, Marion Regnier, Raphael Denis, Catherine Postic, Anthony Novell, Jean-Luc Gennisson

Abstract read
In one paragraph

Article in Journal of ultrasound in medicine : official journal of the American Institute of Ultrasound in Medicine, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Gilles RenaultUniversité Paris Cité, CNRS, Inserm, Institut Cochin, Paris, France.
Lenin ChinchillaLaboratoire d'Imagerie Biomédicale Multimodales à Paris-Saclay, BioMaps, Université Paris-Saclay, Orsay, France.
Lourdes MassengoUniversité Paris Cité, CNRS, Inserm, Institut Cochin, Paris, France.
Pierre MonbernardUniversité Paris Cité, CNRS, Inserm, Institut Cochin, Paris, France.
Fadila BenhamedUniversité Paris Cité, CNRS, Inserm, Institut Cochin, Paris, France.
Marion RegnierUniversité Paris Cité, CNRS, Inserm, Institut Cochin, Paris, France.ORCID https://orcid.org/0000-0002-5005-0597
Raphael DenisUniversité Paris Cité, CNRS, Inserm, Institut Cochin, Paris, France.ORCID https://orcid.org/0000-0002-7677-7460
Catherine PosticUniversité Paris Cité, CNRS, Inserm, Institut Cochin, Paris, France.
Anthony NovellLaboratoire d'Imagerie Biomédicale Multimodales à Paris-Saclay, BioMaps, Université Paris-Saclay, Orsay, France.
Jean-Luc GennissonLaboratoire d'Imagerie Biomédicale Multimodales à Paris-Saclay, BioMaps, Université Paris-Saclay, Orsay, France.

Funding

France Life Imaging ANR-11-INBS-0006IBISA consortiumITMO Cancer of AviesanSIRIC CARPEM INCa-DGOS-Inserm-ITMO Cancer_18006
6 · The paper itself

Abstract

objectivesO-GlcNAcylation plays a key regulatory role in hepatic physiology, and its disruption leads to fibrosis in liver-specific OGT knockout mice (OGT

methodsWe weekly monitored non-invasively liver fibrosis progression in OGT

resultsWeekly liver stiffness measurements demonstrated a progressive increase, correlating strongly with histological fibrosis scores (R

conclusionOur study confirms that following liver stiffness fibrosis by SWE in a mouse model of liver injury is a valuable tool that correlates with ex vivo findings. This approach facilitates a better understanding of disease progression and therapeutic evaluation in preclinical models of MASH.

Indexed as

Elasticity Imaging TechniquesLiver CirrhosisAnimalsDisease Models, AnimalDisease ProgressionLiverMiceMice, Inbred C57BLMice, Knockoutliver fibrosis stageliver stiffnessOGTLKOshear wave elastography

Identifiers

PMID41342519
PMCPMC13053628

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.