Evidence map›Paper›PMID 41342228›Full record

ArticleVirulence2025

YTHDC2 promotes sepsis-induced cardiomyopathy by activating apoptosis and NF-κB pathway.

Wei Wang, Tie-Ning Zhang, Zi-Mu Wang, Ni Yang, Chun-Feng Liu

Abstract read
In one paragraph

Article in Virulence, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Wei WangDepartment of Pediatrics, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, China.
Tie-Ning ZhangDepartment of Pediatrics, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, China.
Zi-Mu WangDepartment of Orthopaedic Surgery, Children's Hospital Affiliated to Zhengzhou University, Henan Children's Hospital, Zhengzhou Children's Hospital, Zhengzhou, Henan, China.
Ni YangDepartment of Pediatrics, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, China.
Chun-Feng LiuDepartment of Pediatrics, Shengjing Hospital of China Medical University, Shenyang, Liaoning Province, China.ORCID 0000-0001-5360-616X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Sepsis-induced cardiomyopathy (SICM) is a severe complication of sepsis, especially in children, and identification of novel therapeutic targets remains essential for improving patient outcomes. Recent studies have implicated N6-methyladenosine (m

Indexed as

CardiomyopathiesNF-kappa BRNA HelicasesSepsisAnimalsApoptosisbcl-2-Associated X Proteinbcl-2 Homologous Antagonist-Killer ProteinCell LineMaleMyocytes, CardiacRatsRats, WistarBak1 protein, ratBax protein, ratbcl-2-Associated X Proteinbcl-2 Homologous Antagonist-Killer ProteinNF-kappa BRNA Helicasesapoptosiscardiacm6AsepsisYTHDC2

Identifiers

PMID41342228
PMCPMC12688274

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.