Evidence map›Paper›PMID 41342187›Full record

ArticleJournal of biological rhythms2026

Regulation of Metabolic Rhythms by Glial Clocks.

Catarina Carvalhas-Almeida, Sara B Noya, Tianqi Wu, Ana Rita Álvaro, Cláudia Cavadas, Julie A Williams, Amita Sehgal

Abstract read
In one paragraph

Article in Journal of biological rhythms, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Catarina Carvalhas-AlmeidaCenter for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal.ORCID 0000-0002-4942-8249
Sara B NoyaDepartment of Neuroscience, Chronobiology and Sleep Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0002-4830-0411
Tianqi WuDepartment of Neuroscience, Chronobiology and Sleep Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0009-0004-8475-4367
Ana Rita ÁlvaroCenter for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal.
Cláudia CavadasCenter for Neuroscience and Cell Biology, University of Coimbra, Coimbra, Portugal.ORCID 0000-0001-8020-9266
Julie A WilliamsDepartment of Neuroscience, Chronobiology and Sleep Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0003-3467-0865
Amita SehgalDepartment of Neuroscience, Chronobiology and Sleep Institute, Perelman School of Medicine, University of Pennsylvania, Philadelphia, Pennsylvania, USA.ORCID 0000-0001-7354-9641

Funding

Interaction between circadian and sleep circuitsR01NS048471 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI AMITA SEHGAL · 2005 to 2026
$4.8M
Cycling in a circadian circuitR37NS048471 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI SEHGAL, AMITA · 2015 to 2021
$2.7M
Cycling of circadium rhythm proteinsR56NS048471 · NINDS · UNIVERSITY OF PENNSYLVANIA · PI SEHGAL, AMITA · 2010 to 2010
$400k
NINDS NIH HHS R01 NS048471NINDS NIH HHS R37 NS048471NINDS NIH HHS R56 NS048471
6 · The paper itself

Abstract

Rhythmicity is a central feature of behavioral and physiological processes, including sleep, immune responses, and metabolism. Research on brain control of these processes has largely focused on neurons, with less known about the role of clock genes in glial cells. In this study, we addressed the function of glial clocks by targeting the expression of key clock genes in glia of

Indexed as

Circadian ClocksCircadian RhythmDrosophila melanogasterNeurogliaAnimalsDrosophila ProteinsEnergy MetabolismFeeding BehaviorGlycogenLocomotionMotor ActivityPeriod Circadian ProteinsSleepDrosophila ProteinsGlycogenPeriod Circadian ProteinsPER protein, Drosophilatim protein, Drosophilacircadian rhythmsclock genesDrosophilafeeding rhythmgliametabolismsleep

Identifiers

PMID41342187
PMCPMC12694984

What OpenQuestion holds

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LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.