Evidence map›Paper›PMID 41342177›Full record

ReviewHaematologica2026

Prognostic factors in chronic myeloid leukemia: at diagnosis and for treatment-free remission.

Delphine Rea

Abstract readReview
In one paragraph

Review in Haematologica, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

1 author.

Delphine ReaDépartement Médico-Universitaire d'Hématologie et Immunologie, Hôpital Saint-Louis, Paris, France; France Intergroupe des Leucémies Myéloïdes Chroniques Fi-LMC, Institut Bergonié, Bordeaux. delphine.rea@aphp.fr.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Although chronic myeloid leukemia (CML) is defined by the sole presence of the BCR::ABL1 fusion gene - the genetic event underlying the genesis of the disease - the diversity of clinical outcomes, even in the tyrosine kinase inhibitor (TKI) era, reveals that its apparent biological homogeneity is, in fact, misleading, both between and within individuals. Increasing knowledge of biological diversity through advances in cellular analytical tools and expansion of the TKI arsenal to address this heterogeneity are key factors in the path to better disease control and ultimately cure. In this review, we focus on well-established and novel modifiable and non-modifiable prognostic factors of CML at diagnosis and for treatment-free remission, with particular emphasis on those that are easy to use in clinical practice. We discuss how these factors may help shape therapeutic choices. Finally, we highlight innovative research avenues aiming at improving prognostication of CML.

Indexed as

Leukemia, Myelogenous, Chronic, BCR-ABL PositiveBiomarkers, TumorFusion Proteins, bcr-ablHumansPrognosisProtein Kinase InhibitorsRemission InductionBiomarkers, TumorFusion Proteins, bcr-ablProtein Kinase Inhibitors

Identifiers

PMID41342177
PMCPMC13317846

What OpenQuestion holds

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LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.