Evidence map›Paper›PMID 41342001›Full record

ArticleJHLT open2026

Fungal colonization and CLAD in lung transplant recipients: Implications for antifungal prophylaxis and graft survival.

Zehra Dhanani, Isam Albaba, Fatima Anjum

Abstract read
In one paragraph

Article in JHLT open, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Zehra DhananiThoracic Medicine and Surgery, Temple University Hospital, Philadelphia, Pennsylvania.
Isam AlbabaThoracic Medicine and Surgery, Temple University Hospital, Philadelphia, Pennsylvania.
Fatima AnjumThoracic Medicine and Surgery, Lewis Katz School of Medicine at Temple University, Philadelphia, Pennsylvania.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Fungal colonization is common after lung transplantation, but its relationship with chronic lung allograft dysfunction (CLAD) remains uncertain. Methods: We conducted a retrospective cohort study of 220 adult lung transplant recipients between 2018 and 2022 at a high-volume transplant center. Colonization was defined by positive respiratory cultures without evidence of invasive fungal infection. The primary outcome was development of bronchiolitis obliterans syndrome (BOS), the predominant phenotype of CLAD. The analytic cohort comprised consecutive recipients meeting inclusion criteria, with exclusions for multiorgan or redo transplant, insufficient follow-up data, and clinically relevant pulmonary infections during follow-up, specifically invasive fungal infection and bacterial pneumonia. Multivariable cox regression models were used to examine associations between colonization and BOS-CLAD. Results: Fungal colonization occurred in 121 of 220 recipients (55%), most commonly Conclusions: In this single-center cohort, fungal colonization-particularly with

Indexed as

Aspergillus colonizationbronchiolitis obliterans syndromegraft survivallung transplantationPseudomonas colonization

Identifiers

PMID41342001
PMCPMC12671345

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.