Evidence map›Paper›PMID 41341996›Full record

ArticleSleep advances : a journal of the Sleep Research Society2025

Serum 25-hydroxyvitamin D concentration is associated with device-estimated sleep metrics in healthy young and early middle-aged adults.

Michele N D'Agata, Elissa K Hoopes, Thomas Keiser, Freda Patterson, Benjamin C Brewer, Melissa A Witman

Abstract read
In one paragraph

Article in Sleep advances : a journal of the Sleep Research Society, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Michele N D'AgataDepartment of Kinesiology and Applied Physiology, College of Health Sciences, University of Delaware, Newark, DE, United States.
Elissa K HoopesDepartment of Health Behavior and Nutrition Sciences, College of Health Sciences, University of Delaware, Newark, DE, United States.ORCID https://orcid.org/0000-0001-6785-7007
Thomas KeiserDepartment of Health Behavior and Nutrition Sciences, College of Health Sciences, University of Delaware, Newark, DE, United States.
Freda PattersonDepartment of Health Behavior and Nutrition Sciences, College of Health Sciences, University of Delaware, Newark, DE, United States.ORCID https://orcid.org/0000-0001-6561-3092
Benjamin C BrewerCenter for Biostatistics and Health Data Science, College of Science, Virginia Polytechnic Institute and State University, Roanoke, VA, United States.
Melissa A WitmanDepartment of Kinesiology and Applied Physiology, College of Health Sciences, University of Delaware, Newark, DE, United States.ORCID https://orcid.org/0000-0002-9003-8779

Funding

Vascular Consequences of Duchenne Muscular DystrophyP20GM113125 · NIGMS · UNIVERSITY OF DELAWARE · PI LENNON, SHANNON L. · 2016 to 2025
$23.3M
NIGMS NIH HHS P20 GM113125
6 · The paper itself

Abstract

Study Objectives: We tested associations between serum 25-hydroxyvitamin D concentration ([25(OH)D]) and device-estimated sleep metrics, including sleep duration, sleep efficiency, sleep duration regularity, sleep timing regularity, and sleep regularity index (SRI), in young and early middle-aged adults (18-45 years). We also assessed the mediating effect of nighttime melatonin (urinary 6-sulfatoxymelatonin (aMT6s) excretion) on these associations. Methods: Participants ( Results: Serum [25(OH)D] was positively associated with sleep duration, sleep efficiency, and SRI, and negatively associated with sleep duration regularity, sleep onset timing regularity, and sleep midpoint timing regularity in model 1 (all Conclusions: Serum [25(OH)D] is independently associated with several sleep metrics in healthy adults. However, nighttime melatonin concentration did not mediate these associations, thus other mechanistic pathways must be considered.

Indexed as

actigraphymelatoninsleepvitamin Dyoung adults

Identifiers

PMID41341996
PMCPMC12670636

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.