Evidence map›Paper›PMID 41341944›Full record

ArticleRevista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia2025

The combination of circulating levels of ANGPTL, omentin-1, leptin and cytokines is associated with polycystic ovary syndrome in different BMI groups.

Rumeysa Çınar, Özlem Kayacık Günday, Ahmet Kahraman, Mehmet Yılmazer

Abstract read
In one paragraph

Article in Revista brasileira de ginecologia e obstetricia : revista da Federacao Brasileira das Sociedades de Ginecologia e Obstetricia, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Rumeysa ÇınarAfyonkarahisar University of Health Sciences Faculty of Medicine Department of Biochemistry Afyonkarahisar Turkey Afyonkarahisar University of Health Sciences, Faculty of Medicine, Department of Biochemistry, Afyonkarahisar, Turkey.ORCID https://orcid.org/0000-0002-6717-7682
Özlem Kayacık GündayAfyonkarahisar University of Health Sciences Faculty of Medicine Department of Obstetrics and Gynecology Afyonkarahisar Turkey Afyonkarahisar University of Health Sciences, Faculty of Medicine, Department of Obstetrics and Gynecology, Afyonkarahisar, Turkey.ORCID https://orcid.org/0000-0002-9249-679X
Ahmet KahramanAfyonkarahisar University of Health Sciences Faculty of Medicine Department of Biochemistry Afyonkarahisar Turkey Afyonkarahisar University of Health Sciences, Faculty of Medicine, Department of Biochemistry, Afyonkarahisar, Turkey.ORCID https://orcid.org/0000-0003-3310-3252
Mehmet YılmazerAfyonkarahisar University of Health Sciences Faculty of Medicine Department of Obstetrics and Gynecology Afyonkarahisar Turkey Afyonkarahisar University of Health Sciences, Faculty of Medicine, Department of Obstetrics and Gynecology, Afyonkarahisar, Turkey.ORCID https://orcid.org/0000-0001-5445-6159

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: This study aims to explore the combined role of ANGPTL3, 4, 8, omentin-1, leptin, TNF-α, and IL-6 molecules known for their roles in fat metabolism, obesity, and inflammation, yet whose connection to PCOS is still debated in the development of PCOS. Methods: A prospective cross-sectional study involving PCOS patients (n=30) and BMI-matched controls (n=30) was conducted. Levels of ANGPTL3, 4, 8, omentin-1, leptin, TNF-α, and IL-6 were measured in peripheral venous blood samples. Results: When dividing both the PCOS and control groups into six BMI-based subgroups normal weight (20-24.9 kg/m Conclusion: This study suggests a continuous interaction among ANGPTL, omentin-1, leptin, and cytokines in the etiopathogenesis of PCOS.

Indexed as

Angiopoietin-like ProteinsBody Mass IndexCytokinesLectinsLeptinPolycystic Ovary SyndromeAdultAngiopoietin-Like Protein 3Cross-Sectional StudiesFemaleGPI-Linked ProteinsHumansProspective StudiesYoung AdultAngiopoietin-Like Protein 3Angiopoietin-like ProteinsANGPTL3 protein, humanCytokinesGPI-Linked ProteinsITLN1 protein, humanLectinsLeptinANGPTLLeptinOmentin-1Polycystic ovary syndrome: Obesity

Identifiers

PMID41341944
PMCPMC12671682

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.