Evidence map›Paper›PMID 41341900›Full record

ArticleJournal of pain research2025

The American Society of Pain and Neuroscience (ASPN) Guidelines for Advanced Practice Providers in Interventional Spine and Pain Management Practice.

Casey Grillo, Alaa Abd-Elsayed, Tariq A Yousef, Brittney Misercola, Zohra Hussaini, Morteza Rabii, Ashley Comer, Kristen Durkin, Patrick McGinn, Timothy Deer

Abstract read
In one paragraph

Article in Journal of pain research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Casey GrilloThe Spine and Pain Institute of New York, New York, NY, USA.
Alaa Abd-ElsayedAnesthesiology Department, University of Wisconsin- Madison, Madison, WI, USA.
Tariq A YousefThe Spine and Pain Institute of New York, New York, NY, USA.
Brittney MisercolaPain Specialists of America, Austin, TX, USA.
Zohra HussainiDepartment of Anesthesiology, the University of Kansas Health System, Kansas City, KS, USA.ORCID 0000-0002-0608-4853
Morteza RabiiCrimson Pain Management, Overland Park, KS, USA.
Ashley ComerThe Spine and Nerve Center of the Virginias in Charleston, Charleston, WV, USA.
Kristen DurkinNY Spine & Pain Specialists, Port Jefferson Station, NY, USA.
Patrick McGinnNational Spine and Pain Centers, Shrewsbury, NJ, USA.
Timothy DeerThe Spine and Nerve Center of the Virginias in Charleston, Charleston, WV, USA.ORCID 0000-0001-8907-7730

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Chronic pain management has advanced with minimally invasive interventions that reduce surgical trauma and recovery time. Specialized interventional spine clinics rely on multidisciplinary approaches to improve outcomes. Advanced Practice Providers (APPs), including nurse practitioners, physician assistants, and clinical nurse specialists, play increasingly important roles in these settings. However, standardized guidance on APP integration, training, and scope of practice remains limited. This guideline, developed by an expert panel, is the first to address APP roles in interventional pain management. It is intended for a broad audience including APPs, physicians, and healthcare administrators/policymakers who are involved in spine and pain management. Methods: In 2024, a multidisciplinary American Society of Pain and Neuroscience (ASPN) panel conducted a targeted literature review and iterative consensus process. Relevant studies, regulations, and guidelines up to 2025 were reviewed. No formal Delphi or grading system was used; recommendations were finalized by group agreement. Topics included APP training, regulatory frameworks, collaborative care models, procedural involvement, medication management, and future directions. Results: The panel identified nine domains central to APP practice. Recommendations emphasize structured specialty training with fellowship-style onboarding and ongoing competency maintenance; collaborative models in which APPs conduct evaluations, education, and peri-/post-procedural care, while physicians perform high-risk interventions; and strict adherence to state, payer, and institutional rules. ASPN does not endorse independent APP performance of advanced interventional procedures. APPs are key to patient safety through pre-procedure risk assessment, informed consent, and complication monitoring, and they play a central role in medication management, including reconciliation, non-opioid therapy, and opioid prescribing under collaborative frameworks with consistent risk-mitigation practices. Limitations include regulation variability, lack of standardized training pathways, and limited APP-specific outcome data. Conclusion: These consensus-based guidelines can expand access, improve safety, and enhance patient satisfaction. Standardizing APP roles and training will allow practices to meet rising demand while maintaining high-quality care. Continued evaluation of APP-driven outcomes and development of formal fellowships and certification pathways will be essential to refine these recommendations.

Indexed as

advanced practice providersclinical nurse specialistguidelinesinterventional painnurse practitionerphysician assistantspine

Identifiers

PMID41341900
PMCPMC12669062

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.