Evidence map›Paper›PMID 41341868›Full record

ReviewInternational journal of nanomedicine2025

Recent Advances in Biomimetic Drug Delivery for Rheumatoid Arthritis Treatment.

Yucheng Xiang, Zongyu Pan, Deyong Tian, Lie Zhang, Wantai Dang, Jing Ye, Xiaohong Xu, Quan Zhang

Abstract readReview
In one paragraph

Review in International journal of nanomedicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Article
  2. Review
  3. Review
  4. Review
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Yucheng Xiang *Department of Neurosurgery, The First Affiliated Hospital of Chengdu Medical College, Chengdu, People's Republic of China.
Zongyu Pan *Department of Neurosurgery, The First Affiliated Hospital of Chengdu Medical College, Chengdu, People's Republic of China.
Deyong TianKey Laboratory of Structure-Specific Small Molecule Drugs, Institute of Materia Medica, School of Pharmacy, Chengdu Medical College, Chengdu, People's Republic of China.
Lie ZhangDepartment of Neurosurgery, The First Affiliated Hospital of Chengdu Medical College, Chengdu, People's Republic of China.
Wantai DangDevelopment and Regeneration Key Laboratory of Sichuan Province, Chengdu Medical College, Chengdu, People's Republic of China.
Jing YeKey Laboratory of Structure-Specific Small Molecule Drugs, Institute of Materia Medica, School of Pharmacy, Chengdu Medical College, Chengdu, People's Republic of China.
Xiaohong XuKey Laboratory of Structure-Specific Small Molecule Drugs, Institute of Materia Medica, School of Pharmacy, Chengdu Medical College, Chengdu, People's Republic of China.
Quan ZhangDepartment of Neurosurgery, The First Affiliated Hospital of Chengdu Medical College, Chengdu, People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Rheumatoid arthritis (RA) affects approximately 1% of the global population, causing debilitating joint pain and often leading to severe disability. Although conventional treatments can control the initial symptoms of RA, there is no curative treatment strategy for RA. Biomimetic nanomedicine has emerged as a promising therapeutic approach, leveraging the integration of nanoparticles with natural biomaterials to achieve targeted drug delivery and improved treatment outcomes. Beyond exogenous nano-delivery systems, the natural biomimetic strategy might offer superior biocompatibility and lower immunogenicity. This review summarizes the latest advancements in biomimetic drug delivery systems for RA and highlights the underlying mechanisms for these biomimetic carriers. We also discuss the critical factors influencing the transition of these biomimetic nanomedicines from laboratory research to clinical implementation. By emphasizing the transformative potential of biomimetic strategies in RA treatment, this review aims to provide new insights and directions for future research and clinical applications in this field.

Indexed as

Antirheumatic AgentsArthritis, RheumatoidBiomimetic MaterialsBiomimeticsDrug Delivery SystemsAnimalsHumansNanomedicineNanoparticlesAntirheumatic Agentsbiomaterialsbiomimetic drug delivery systemrheumatoid arthritistargeting therapy

Identifiers

PMID41341868
PMCPMC12671108

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.