ArticleFrontiers in medicine2025
Antimicrobial resistance profiles in septic arthritis of native knee and shoulder joints from 2007 to 2024: a single center retrospective study.
Article in Frontiers in medicine, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Introduction: Septic arthritis of large joints is associated with high morbidity and mortality, necessitating prompt empiric antibiotic therapy tailored to local and current pathogen patterns. The need for antimicrobial stewardship further highlights the importance of updated data on pathogens and resistance trends to guide effective empiric treatment. Methods: This study retrospectively investigated the distribution of causative pathogens and their antimicrobial resistance profiles in septic arthritis of native knee and shoulder joints from January 2007 to December 2024 at a tertiary hospital. A total of 326 patients who met the modified Newman Criteria and had confirmed culture results with antimicrobial susceptibility data were included. Cases involving prosthetic joints, treatment initiated at other facilities, or incomplete records were excluded. Cases were grouped into three six-year intervals to evaluate temporal trends in pathogen distribution and antimicrobial resistance. Results: Discussion: Our data support the empirical use of narrow spectrum beta-lactams for septic arthritis of the knee and shoulder.
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