ArticleAsia Pacific allergy2025
Oral symptoms suggestive of oral allergy syndrome in Japanese schoolchildren according to causative food families.
Article in Asia Pacific allergy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers, 1 of them a synthesis that pooled it.
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Who cites it
2 citing papers in PubMed, 1 synthesis or guideline pooled it.
- From systemic immune dysregulation to oral disease: evidence linking food allergies and oral manifestations- a systematic review.BMC oral health · 2026Pooled it
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Authors and funding
5 authors.
Funding
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Abstract
Background: Oral allergy syndrome (OAS) is an immediate allergic reaction triggered by specific foods, often linked to pollen-food allergy syndrome (PFAS). With the increasing prevalence of pollinosis in Japan, especially among younger populations, OAS and PFAS are expected to rise. However, few studies have investigated their prevalence in pediatric populations, particularly in relation to different families of causative foods. Objective: In this study, we examined the comparative prevalences of oral symptoms suggestive of OAS based on survey data from parents of a general population of children attending elementary and junior high schools, focusing on the differences between causative food families. Methods: We conducted a questionnaire-based survey among parents of 6,853 elementary and junior high school students in Omihachiman, Japan. Oral symptom was identified based on reported oral symptoms following the consumption of specific raw fruits and vegetables. Data were analyzed using trend analysis and multivariable logistic regression. Results: Among 4,991 respondents (72.8%), 12.4% had oral symptoms. Prevalence was significantly higher in females than in males (14.4% vs. 10.4%). Older age groups showed higher prevalence trends, except for Cucurbitaceae (melon/watermelon). Actinidiaceae (kiwi) and Bromeliaceae (pineapple) had significantly higher prevalence in females, while Cucurbitaceae (melon/watermelon) showed no sex differences. No significant sex differences were observed in cases requiring avoidance. Conclusion: This study provides the first prevalence estimates of oral symptoms suggestive of OAS by sex, age, and causative food family in Japanese children. These findings contribute to improved diagnosis, treatment, and prevention strategies for pediatric OAS and PFAS.
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