Evidence map›Paper›PMID 41341645›Full record

ReviewActa gastroenterologica Latinoamericana

[Precision Medicine in the Primary and Secondary Prevention of Gastric Cancer].

Irina Luzko, Patricio Medel-Jara, Joan Llach, Diego Reyes, Leticia Moreira, Arnoldo Riquelme

Abstract readEnglish AbstractReview
In one paragraph

Review in Acta gastroenterologica Latinoamericana. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Irina LuzkoHospital Clínic de Barcelona, Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBERehd), IDIBAPS (Institut d'Investigacions Biomèdiques August Pi i Sunyer), Universidad de Barcelona, Barcelona, Spain. Universitat Autónoma de Barcelona Hospital Clínic de Barcelona, Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBERehd) IDIBAPS (Institut d'Investigacions Biomèdiques August Pi i Sunyer) Universidad de Barcelona, Barcelona Spain.ORCID https://orcid.org/0000-0002-8292-1596
Patricio Medel-JaraPrograma de Farmacología y Toxicología, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile. Pontificia Universidad Católica de Chile Programa de Farmacología y Toxicología Facultad de Medicina Pontificia Universidad Católica de Chile Santiago Chile.ORCID https://orcid.org/0000-0003-3784-1463
Joan LlachHospital Clínic de Barcelona, Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBERehd), IDIBAPS (Institut d'Investigacions Biomèdiques August Pi i Sunyer), Universidad de Barcelona, Barcelona, Spain. Universitat Autónoma de Barcelona Hospital Clínic de Barcelona, Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBERehd) IDIBAPS (Institut d'Investigacions Biomèdiques August Pi i Sunyer) Universidad de Barcelona, Barcelona Spain.ORCID https://orcid.org/0000-0001-6535-8925
Diego ReyesDepartamento de Gastroenterología, Facultad de Medicina, Pontificia Universidad Católica de Chile, Santiago, Chile. Pontificia Universidad Católica de Chile Departamento de Gastroenterología Facultad de Medicina Pontificia Universidad Católica de Chile Santiago Chile.ORCID https://orcid.org/0000-0001-6371-3516
Leticia MoreiraHospital Clínic de Barcelona, Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBERehd), IDIBAPS (Institut d'Investigacions Biomèdiques August Pi i Sunyer), Universidad de Barcelona, Barcelona, Spain. Universitat Autónoma de Barcelona Hospital Clínic de Barcelona, Centro de Investigación Biomédica en Red en Enfermedades Hepáticas y Digestivas (CIBERehd) IDIBAPS (Institut d'Investigacions Biomèdiques August Pi i Sunyer) Universidad de Barcelona, Barcelona Spain.ORCID https://orcid.org/0000-0002-4518-8591
Arnoldo RiquelmeCentro de Control y Prevención del Cáncer (CECAN), Santiago, Chile. Centro de Control y Prevención del Cáncer (CECAN) Santiago Chile.ORCID https://orcid.org/0000-0002-8259-8960

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gastric cancer is one of the most frequent cancers worldwide. It has a poor prognosis associated with late-stage diagnosis, that significantly decreases overall survival. This highlights the importance of prevention and early detection to improve the clinical course of patients. Prevention and early diagnosis of gastric cancer perfectly exemplify the model of precision medicine, a healthcare approach that seeks to place the burden more on the individual than on the general population. This requires not only a comprehensive knowledge of the disease but also the identification of individual factors and the understanding of genetic, molecular and environmental differences, which are key to the development of much more personalized treatment strategies. With this approach, in gastric cancer prevention the subject is always at the center, the measures focus directly on the individual and, secondarily, lead to the optimization of the use of resources. This review briefly discusses primary prevention strategies for gastric cancer based on detection and eradication of Helicobacter pylori and, on the other hand, describes some of the most promising biomarkers for the detection and diagnosis of early gastric cancer identified in blood, saliva, urine, feces, and gastric juice, all of which are components of potential secondary prevention measures.

Indexed as

biomarkersGastric cancerHelicobacter pyloriprecision medicineprimary preventionsecondary prevention

Identifiers

PMID41341645
PMCPMC12500183

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.