Evidence map›Paper›PMID 41341565›Full record

ArticleClinical case reports2025

Zanubrutinib Combined With Rituximab in the Treatment of Bing-Neel Syndrome: A Case Report.

Rongyao Zhang, Juan Chang, Yanqun Shen, Ping Hu, Lulu Zhang

Abstract read
In one paragraph

Article in Clinical case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rongyao ZhangDepartment of Hematology, Taihe Hospital Hubei University of Medicine Shiyan Hubei People's Republic of China.ORCID https://orcid.org/0009-0001-0409-4062
Juan ChangDepartment of Hematology, Taihe Hospital Hubei University of Medicine Shiyan Hubei People's Republic of China.
Yanqun ShenDepartment of Hematology, Taihe Hospital Hubei University of Medicine Shiyan Hubei People's Republic of China.
Ping HuDepartment of Hematology, Taihe Hospital Hubei University of Medicine Shiyan Hubei People's Republic of China.
Lulu ZhangDepartment of Hematology, Taihe Hospital Hubei University of Medicine Shiyan Hubei People's Republic of China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Bing-Neel syndrome (BNS) is a rare complication of Waldenström macroglobulinemia, a condition with low incidence in clinical practice and prone to misdiagnosis. Vigilance is crucial for identifying this condition in patients with Waldenström macroglobulinemia presenting with neurological symptoms. In cases where a pathological biopsy is inconclusive, cerebrospinal fluid flow cytometry can be utilized to aid in diagnosis. Currently, there is no established standard treatment protocol for BNS, and treatment outcomes vary. In this study, a combination of zanubrutinib and R-CHOP regimen was administered, with zanubrutinib being continued for the management of BNS, resulting in a notably favorable response.

Indexed as

anti‐CD20 monoclonal antibodyBing–Neel syndromeflow cytometryWaldenström macroglobulinemiazanubrutinib

Identifiers

PMID41341565
PMCPMC12669074

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.