Evidence map›Paper›PMID 41341559›Full record

ArticleCureus2025

Relationship Between Short-Term Postural Responses to Noisy Galvanic Vestibular Stimulation at Varying Current Intensities and Its Prolonged Effects in Patients With Peripheral Vestibulopathy.

Chisato Fujimoto, Takuya Kawahara, Yayoi S Kikkawa, Makoto Kinoshita, Teru Kamogashira, Mineko Oka, Kentaro Ichijo, Kenji Kondo, Shinichi Iwasaki

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Trial
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Chisato FujimotoOtorhinolaryngology and Head and Neck Surgery, The University of Tokyo, Bunkyo, JPN.
Takuya KawaharaClinical Research Promotion Center, The University of Tokyo Hospital, Bunkyo, JPN.
Yayoi S KikkawaOtorhinolaryngology and Head and Neck Surgery, The University of Tokyo, Bunkyo, JPN.
Makoto KinoshitaOtorhinolaryngology and Head and Neck Surgery, The University of Tokyo, Bunkyo, JPN.
Teru KamogashiraOtorhinolaryngology and Head and Neck Surgery, The University of Tokyo, Bunkyo, JPN.
Mineko OkaOtorhinolaryngology and Head and Neck Surgery, The University of Tokyo, Bunkyo, JPN.
Kentaro IchijoOtorhinolaryngology and Head and Neck Surgery, The University of Tokyo, Bunkyo, JPN.
Kenji KondoOtorhinolaryngology and Head and Neck Surgery, The University of Tokyo, Bunkyo, JPN.
Shinichi IwasakiOtorhinolaryngology and Head and Neck Surgery, The University of Tokyo, Bunkyo, JPN.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesFor patients with peripheral vestibulopathy, the optimal intensity of noisy galvanic vestibular stimulation (nGVS) for improving postural stability can vary from day to day, yet frequent measurement is clinically challenging. This study aimed to investigate the relationship between the short-term effects of nGVS at various current intensities on postural stability and the prolonged effects of nGVS applied at the optimal intensity on different days. Specifically, we sought to identify which short-term nGVS intensities were effective in patients who showed improvement with prolonged nGVS.

methodsThis trial registration was registered on August 10, 2018, (number: jRCT1080224083). Patients with peripheral vestibulopathy underwent closed-eye center-of-pressure (COP) measurements for 30 seconds without nGVS and with nGVS at 100-2000 μA to determine the optimal intensity (defined as the current yielding the greatest velocity improvement). Prolonged nGVS was then applied at this optimal intensity. Patients demonstrating at least a 10% improvement in mean velocity change during three hours of stimulation compared with placebo were classified as the "improvement" group, while others formed the "no-improvement" group. The percent change in COP velocity from baseline (no nGVS) at each intensity was compared between groups.

resultsThe improvement group (n = 9) demonstrated significantly greater reductions in COP velocity than the no-improvement group (n = 30) at 100 μA and 1700 μA (

conclusionIn patients with peripheral vestibulopathy, the beneficial effect of prolonged nGVS on standing postural control is closely related to short-term responsiveness to nGVS across a wide range of current intensities. In particular, when the optimal stimulation intensity lies between 100 and 1700 μA, this relationship appears strongest.

Indexed as

electric stimulationposturevestibular diseasesvestibular systemvestibule

Identifiers

PMID41341559
PMCPMC12669940

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.