Evidence map›Paper›PMID 41341545›Full record

ArticleBrain communications2025

Lack of epistatic interaction of

Prabhjyot Saini, Eric Yu, Mehrdad A Estiar, Lynne Krohn, Kheireddin Mufti, Uladzislau Rudakou, Jennifer A Ruskey, Farnaz Asayesh, Sandra B Laurent, Dan Spiegelman and 39 more

Abstract read
In one paragraph

Article in Brain communications, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

49 authors.

Prabhjyot SainiMontreal Neurological Institute, McGill University, Montreal, Quebec, Canada H3A 1A1.
Eric YuMontreal Neurological Institute, McGill University, Montreal, Quebec, Canada H3A 1A1.
Mehrdad A EstiarMontreal Neurological Institute, McGill University, Montreal, Quebec, Canada H3A 1A1.
Lynne KrohnMontreal Neurological Institute, McGill University, Montreal, Quebec, Canada H3A 1A1.ORCID https://orcid.org/0000-0001-6554-1666
Kheireddin MuftiMontreal Neurological Institute, McGill University, Montreal, Quebec, Canada H3A 1A1.ORCID https://orcid.org/0000-0002-0447-9624
Uladzislau RudakouMontreal Neurological Institute, McGill University, Montreal, Quebec, Canada H3A 1A1.
Jennifer A RuskeyMontreal Neurological Institute, McGill University, Montreal, Quebec, Canada H3A 1A1.
Farnaz AsayeshMontreal Neurological Institute, McGill University, Montreal, Quebec, Canada H3A 1A1.
Sandra B LaurentCHU Sainte Justine, University of Montreal, Montreal, Quebec, Canada H3T 1C5.
Dan SpiegelmanMontreal Neurological Institute, McGill University, Montreal, Quebec, Canada H3A 1A1.
Isabelle ArnulfSleep Disorders Unit, Pitié-Salpêtrière Hospital, Centre de Recherche de l'Institut du Cerveau et de la Moelle Épinière, and Sorbonne Universités, Paris 75013, France.ORCID https://orcid.org/0000-0002-2240-2516
Jacques Y MontplaisirCentre d'Études Avancées en Médecine du Sommeil, Hôpital du Sacré-Cœur de Montréal, Montreal, Quebec, Canada H4J 1C5.
Jean-François GagnonCentre d'Études Avancées en Médecine du Sommeil, Hôpital du Sacré-Cœur de Montréal, Montreal, Quebec, Canada H4J 1C5.
Alex DesautelsCentre d'Études Avancées en Médecine du Sommeil, Hôpital du Sacré-Cœur de Montréal, Montreal, Quebec, Canada H4J 1C5.
Yves DauvilliersNational Reference Center for Narcolepsy, Sleep Unit, Department of Neurology, Gui-de-Chauliac Hospital, Centre Hospitalier Universitaire Montpellier, University of Montpellier, INSERM U1061, Montpellier 34090, France.ORCID https://orcid.org/0000-0003-0683-6506
Gian Luigi GigliClinical Neurology Unit, Department of Head and Neck, University Hospital of Udine, Udine 33100, Italy.
Mariarosaria ValenteClinical Neurology Unit, Department of Head and Neck, University Hospital of Udine, Udine 33100, Italy.
Francesco JanesClinical Neurology Unit, Department of Head and Neck, University Hospital of Udine, Udine 33100, Italy.
Andrea BernardiniClinical Neurology Unit, Department of Head and Neck, University Hospital of Udine, Udine 33100, Italy.
Karel ŠonkaDepartment of Neurology and Centre of Clinical Neuroscience, First Faculty of Medicine and General University Hospital, Charles University, Prague 121 08, Czech Republic.
David KemlinkDepartment of Neurology and Centre of Clinical Neuroscience, First Faculty of Medicine and General University Hospital, Charles University, Prague 121 08, Czech Republic.ORCID https://orcid.org/0000-0003-1398-5796
Wolfgang H OertelDepartment of Neurology, Philipps University Marburg, Marburg 35032, Germany.ORCID https://orcid.org/0000-0002-7582-8166
Karri KaivolaNeurodegenerative Diseases Research Section, National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892, USA.ORCID https://orcid.org/0000-0003-1218-4014
Annette JanzenDepartment of Neurology, Philipps University Marburg, Marburg 35032, Germany.ORCID https://orcid.org/0000-0001-8907-5831
Giuseppe PlazziDepartment of Biomedical and Neuromotor Sciences (DIBINEM), Alma Mater Studiorum-University of Bologna, Bologna 40126, Italy.
Elena AntelmiDepartment of Engineering and Medicine of Innovation (DIMI), University of Verona, Verona 37134, Italy.
Francesco BiscariniDepartment of Biomedical and Neuromotor Sciences (DIBINEM), Alma Mater Studiorum-University of Bologna, Bologna 40126, Italy.
Michela FigorilliDepartment of Medical Sciences and Public Health, Sleep Disorder Research Center, University of Cagliari, Cagliari 09042, Italy.
Monica PulighedduDepartment of Medical Sciences and Public Health, Sleep Disorder Research Center, University of Cagliari, Cagliari 09042, Italy.
Brit MollenhauerParacelsus-Elena-Klinik, Kassel 34128, Germany.
Claudia TrenkwalderParacelsus-Elena-Klinik, Kassel 34128, Germany.
Friederike Sixel-DöringDepartment of Neurology, Philipps University Marburg, Marburg 35032, Germany.
Valérie Cochen De CockSleep and Neurology Unit, Beau Soleil Clinic, Montpellier 34070, France.
Christelle Charley MonacaDepartment of Clinical Neurophysiology and Sleep Center, University of Lille Nord de France, Centre Hospitalier Universitaire Lille, Lille 59045, France.
Anna HeidbrederDepartment of Neurology and Clinical Research Institute for Neuroscience, Johannes Kepler University Linz, Linz 4020, Austria.
Luigi Ferini-StrambiDepartment of Neurological Sciences, Università Vita-Salute San Raffaele, Milan 20132, Italy.
Femke DijkstraLaboratory for Sleep Disorders, Sint-Dimpna Regional Hospital, Geel 2440, Belgium.
Mineke ViaeneLaboratory for Sleep Disorders, Sint-Dimpna Regional Hospital, Geel 2440, Belgium.
Beatriz AbrilSleep Disorder Unit, Carémeau Hospital, Centre Hospitalier Universitaire Nîmes, Nîmes 30029, France.
Bradley F BoeveDepartment of Neurology, Mayo Clinic, Rochester, MN 55905, USA.ORCID https://orcid.org/0000-0002-4153-8187
Ronald B PostumaMontreal Neurological Institute, McGill University, Montreal, Quebec, Canada H3A 1A1.
Guy A RouleauMontreal Neurological Institute, McGill University, Montreal, Quebec, Canada H3A 1A1.ORCID https://orcid.org/0000-0001-8403-1418
Victoria AnselmiNational Reference Center for Narcolepsy, Sleep Unit, Department of Neurology, Gui-de-Chauliac Hospital, Centre Hospitalier Universitaire Montpellier, University of Montpellier, INSERM U1061, Montpellier 34090, France.
Abubaker IbrahimSleep Disorders Clinic, Department of Neurology, Medical University of Innsbruck, Innsbruck 6020, Austria.ORCID https://orcid.org/0000-0002-0544-030X
Ambra StefaniSleep Disorders Clinic, Department of Neurology, Medical University of Innsbruck, Innsbruck 6020, Austria.ORCID https://orcid.org/0000-0003-4259-8824
Birgit HöglSleep Disorders Clinic, Department of Neurology, Medical University of Innsbruck, Innsbruck 6020, Austria.
Michele T M HuOxford Parkinson's Disease Centre, University of Oxford, Oxford OX1 3QX, UK.ORCID https://orcid.org/0000-0001-6382-5841
Sonja W ScholzNeurodegenerative Diseases Research Section, National Institute of Neurological Disorders and Stroke, Bethesda, MD 20892, USA.ORCID https://orcid.org/0000-0002-6623-0429
Ziv Gan-OrMontreal Neurological Institute, McGill University, Montreal, Quebec, Canada H3A 1A1.ORCID https://orcid.org/0000-0003-0332-234X

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Two recent studies suggested that the

Indexed as

dementia with Lewy bodiesepistasisParkinson’s diseaseREM sleep behaviour disordersynucleinopathies

Identifiers

PMID41341545
PMCPMC12670254

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.