ArticleInternational medical case reports journal2025
Successful Non-Invasive Management of Near-Fatal Asthma with Severe Hypercapnic Respiratory Failure: A Case Report.
Article in International medical case reports journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
Background: Asthma exacerbations can be life-threatening if not promptly recognized and treated. Although necessary, intubation and mechanical ventilation can cause barotrauma, hemodynamic instability, and increased mortality. Documenting near-fatal asthma case with severe hypercapnia, recovering without intubation is uncommon and offers useful clinical insight. Case Presentation: A 45-year-old Somali woman with poorly controlled bronchial asthma presented to the emergency department with acute severe dyspnea following a three-day prodrome of fever, cough, rhinorrhea, and sore throat. On arrival, she was semi-conscious, in respiratory distress, with a silent chest, hypoxemia (SpO Discussion: For life-threatening asthma, GINA, BTS/SIGN, and ERS/ATS recommend systemic corticosteroids, frequent bronchodilators, and intravenous magnesium sulfate as the main treatment, with intubation reserved for respiratory collapse. This case sheds light on how severe hypercapnic respiratory failure patients can recover without invasive airway procedures in resource-limited emergency settings with timely, guideline-adherent care. Conclusion: Early non-invasive treatments for life-threatening asthma can provide positive outcomes, even in near-fatal asthma cases. Intubation and related risks were avoided through close supervision, timely corticosteroids, nebulized bronchodilators, and intravenous magnesium sulfate.
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