ReviewFrontiers in oncology2025
Optimizing data linkage for maximizing the potential of Luxembourg's national cancer registry: a comprehensive scoping review.
Review in Frontiers in oncology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed.
- Understanding return to work after breast cancer through real-world data linkage framework: a Luxembourg digital oncology use case.ESMO real world data and digital oncology · 2026Article
- CancerWatch: accelerating Europe's cancer intelligence.Acta oncologica (Stockholm, Sweden) · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Population-based cancer registries (PBCRs) provide international standardized indicators and evaluate public health actions and cancer care. Their research potential can be significantly enhanced through linkage with secondary data sources, such as biobanks, sociodemographic or genomic data. However, legal, ethical, and technical challenges often hinder such integration. This scoping review aims at identifying data linkage opportunities between cancer registries and secondary data sources, while describing the current state of the Luxembourg's National Cancer Registry (RNC). Ultimately, steps for linkages between cancer registries and biobanks and/or sociodemographic data are assessed to enhance cancer research and public health initiatives. A scoping review using PubMed and Embase databases was performed. English guidelines, reports, and qualitative and quantitative studies on hospital-based cancer registries, PBCRs, and site-specific registries were included. One thousand three hundred and twelve articles (n = 1312) were identified. After scanning titles and abstracts, 49 articles were examined for full-text reading, where fifteen articles met the inclusion criteria. Moreover, 13 articles were included following the snowball search approach (n = 28). Included articles report significant differences between countries in all avenues, including data availability and harmonization, confidentiality, access to data, exchange, and linkage methods. Results underline that PBCR's potential, efficiency, and cost-effectiveness are maximized thanks to linkage activities with secondary data sources such as biobanks or sociodemographic databases. In addition, the results of this scoping review enable the identification of key questions to address before establishing data linkage grouped into five domains being: (i) legal permission, (ii) data availability assessment, (iii) data flow protocol, (iv) linkage key and (v) linkage method. In conclusion, addressing the five key domains identified in this review will support the development of robust, efficient, and ethically sound data linkage strategies, unlocking the full research potential of PBCRs and to aid decision making.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.