Evidence map›Paper›PMID 41341347›Full record

ArticleCureus2025

Breast Primary Follicular Lymphoma: Two Cases of a Rare Entity Treated With Radical Radiotherapy and Rituximab.

Luísa Samarão, José Mário Mariz, Joana Gonçalves, Ângelo Martins, Carla Castro

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Luísa SamarãoRadiation Oncology, Portuguese Oncology Institute of Porto, Porto, PRT.
José Mário MarizHematology and Bone Marrow Transplantation, Portuguese Oncology Institute of Porto, Porto, PRT.
Joana GonçalvesRadiation Oncology, Portuguese Oncology Institute of Porto, Porto, PRT.
Ângelo MartinsHematology and Bone Marrow Transplantation, Portuguese Oncology Institute of Porto, Porto, PRT.
Carla CastroRadiation Oncology, Portuguese Oncology Institute of Porto, Porto, PRT.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Primary breast lymphoma (PBL) is a rare form of non-Hodgkin's lymphoma (NHL), characterized by lymphoma primarily affecting the breast tissue and not seen anywhere else in the body. Follicular breast lymphoma, a distinct histological variant of NHL, manifests with an even greater rarity within the context of breast tissue. The optimal therapeutic approach for these tumors remains controversial. Two cases of follicular lymphoma of the breast are hereby reported. The patients, aged 58 and 56 years, presented at the institution with a breast lump. A biopsy was subsequently performed, yielding a diagnosis of follicular lymphoma. The subjects underwent a positron emission tomography (PET)-computed tomography (CT) scan, which revealed hypermetabolic uptake in the respective breast nodules, with no further alterations. Consequently, they were staged as stage IE. Patients were offered a course of radical radiotherapy with concomitant rituximab. PET-CT scans five months after treatment from both patients revealed a complete metabolic response. In conclusion, we emphasize the role of radiotherapy and rituximab in the management of follicular breast lymphoma.

Indexed as

breastmanagementprimary follicular lymphomaradiotherapyrituximab

Identifiers

PMID41341347
PMCPMC12669936

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.