Evidence map›Paper›PMID 41341336›Full record

ArticleCureus2025

Recovery of Oculomotor Nerve Palsy After Treatment of Posterior Communicating Artery Aneurysms: Have the Outcomes Changed?

Neha Ramu, Swati Jain, Tamara Tajsic, Samir Matloob, Daniel Brown, Mathew Guilfoyle, Adel Helmy, Rikin Trivedi

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Neha RamuNeurology, Guy's and St Thomas' NHS Foundation Trust, London, GBR.
Swati JainNeuroscience, University of Cambridge, Cambridge, GBR.
Tamara TajsicNeurosurgery, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, GBR.
Samir MatloobNeurosurgery, Oxford University Hospitals NHS Foundation Trust, Oxford, GBR.
Daniel BrownNeurosurgery, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, GBR.
Mathew GuilfoyleNeurosurgery, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, GBR.
Adel HelmyNeurosurgery, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, GBR.
Rikin TrivediNeurosurgery, Addenbrooke's Hospital, Cambridge University Hospitals NHS Foundation Trust, Cambridge, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction It is unclear whether microsurgical clipping or endovascular coiling is the best treatment for recovery from oculomotor nerve palsy (ONP) secondary to posterior communicating artery (PComm) aneurysm. This is a five-year study of aneurysms presenting with ONP and their outcomes after treatment. Method The study included all patients from 2017-2022 who presented to a tertiary care centre in the United Kingdom with complete or partial ONP from ruptured or unruptured PComm aneurysms. Electronic medical records of these patients were compared with data from the same unit of an earlier cohort of patients. Results A total of 165 patients with PComm aneurysms were identified in the five-year period. Of these, 30 presented with ONP, of which 17 were complete. A total of 20 patients presented with a subarachnoid haemorrhage; 10 patients underwent microsurgical clipping, and 40% of them had improved ONPs at six months, whereas only 20% of the coiling group improved. The odds ratio of full recovery of ONP with coiling was 0.20 (0.03-1.07) when compared to clipping. Overall, these results were largely similar to those of the earlier cohort; however, this study noted a difference in the rate of recovery depending on treatment modality, albeit not statistically significant. Conclusion No significant difference in rates of recovery of ONPs was found between surgical clipping or endovascular coiling, although this conclusion is limited by the small sample size. Both modalities continue to appear equally effective for aneurysm management.

Indexed as

aneurysmal subarachnoid haemorrhageendovascular coilingoculomotor nerve palsyposterior communicating artery aneurysmsurgical clipping

Identifiers

PMID41341336
PMCPMC12671929

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.