Evidence map›Paper›PMID 41341311›Full record

ArticleFrontiers in plant science2025

Genome-wide identification and functional validation of sterol C-22 desaturases and C-24 methyltransferases in

Sylvia E Brown, Yunbin Li, Chun Lin, Zhengjie Liu, Zichao Mao

Abstract read
In one paragraph

Article in Frontiers in plant science, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Polysaccharides fromFrontiers in pharmacology · 2026
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Sylvia E BrownCollege of Agronomy and Biotechnology, Yunnan Agricultural University (YNAU), Kunming, China.
Yunbin LiCollege of Agronomy and Biotechnology, Yunnan Agricultural University (YNAU), Kunming, China.
Chun LinCollege of Agronomy and Biotechnology, Yunnan Agricultural University (YNAU), Kunming, China.
Zhengjie LiuCollege of Agronomy and Biotechnology, Yunnan Agricultural University (YNAU), Kunming, China.
Zichao MaoCollege of Agronomy and Biotechnology, Yunnan Agricultural University (YNAU), Kunming, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: Steroids are essential components of plant membranes and serve as precursors of brassinosteroids (BRs) and Steroidal saponins (SSs), which regulate growth, development and stress adaptation. Sterol-modifying enzymes, including C-22 desaturases (C22SDs) and C-24 methyltransferases (C24SMTs), act as key branch-point regulators of side-chain remodeling, yet their molecular roles in Methods: Functional genomics analysis of C22SD and C24SMT families was conducted in Results: To overcome transformation barriers in Discussion: By characterizing sterol side-chain remodeling enzymes, this study establishes a framework for understanding the potential roles of these enzymes in membrane stability, hormone biosynthesis and defense metabolite production, with implications for stress resilience and metabolic engineering. These findings highlight sterol remodeling as a potential target for developing stress-resilient crops.

Indexed as

Asparagus officinalisAsparagus taliensisexpression profilingfunctional genomicssterol biosynthesissterol C-22 desaturasesterol C-24 methyltransferasestress resilience

Identifiers

PMID41341311
PMCPMC12671487

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.