Evidence map›Paper›PMID 41341283›Full record

ArticleAJOG global reports2025

Quantifying maternal vaccination opportunities across gestational age windows: a real-world multi-country, longitudinal study.

Rachel Ford, Oluwatosin Nkereuwem, Ugochukwu Madubueze, Urudinachi Agbo, Suraj Bhattarai, Rabin Thami, Dan Kajungu, Victoria Nambasa, Agnes Msoka, Mir Mobarak Hossain and 2 more

Abstract read
In one paragraph

Article in AJOG global reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Rachel FordDepartment of Clinical Research, London School of Hygiene & Tropical Medicine (Ford, Bhattarai, and Kampmann), London, UK.
Oluwatosin NkereuwemMedical Research Council Unit, The Gambia at the London School of Hygiene and Tropical Medicine (Nkereuwem and Kampmann), Fajara, The Gambia.
Ugochukwu MadubuezeNational Obstetric Fistula Centre, Abakaliki, Nigeria (Madubueze).
Urudinachi AgboAlex Ekwueme Federal University Teaching Hospital, Abakaliki, Nigeria (Madubueze and Agbo).
Suraj BhattaraiDepartment of Clinical Research, London School of Hygiene & Tropical Medicine (Ford, Bhattarai, and Kampmann), London, UK.
Rabin ThamiGlobal Health Research and Medical Interventions Institute, Nepal (Bhattarai and Thami).
Dan KajunguMakerere University Centre for Health and Population Research, Kampala (Kajungu).
Victoria NambasaAfrican Union Development Agency, Johannesburg, South Africa (Nambasa).
Agnes MsokaKilimanjaro Clinical Research Institute (Msoka), Moshi, Kilimanjaro, Tanzania.
Mir Mobarak HossainPlanning and Research Unit, Directorate General of Health Services, Dhaka, Bangladesh (Hossain).
Edward P K ParkerDepartment for Infectious Disease Epidemiology and International Health, London School of Hygiene and Tropical Medicine (Parker), London, UK.
Beate KampmannDepartment of Clinical Research, London School of Hygiene & Tropical Medicine (Ford, Bhattarai, and Kampmann), London, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Maternal vaccination is a recognized strategy for reducing maternal and neonatal morbidity and mortality, including in low- and middle-income countries (LMICs). As new vaccines such as those for respiratory syncytial virus (RSV) and group B streptococcus (GBS) will be administered according to gestational age (GA), understanding real-world patterns of contact of pregnant women with antenatal care services (ANC) across pregnancy is essential to inform the most effective delivery strategies. Methods: We conducted a retrospective longitudinal, multisite analysis using anonymized data extracted from maternal health registers at ANC and delivery clinics in 6 LMICs: Bangladesh, The Gambia, Nepal, Nigeria, Tanzania, and Uganda. Eligible clinics contributed data from ANC and delivery services and access to routine data from January 2019 to December 2022. Retrospective, individual-level ANC attendance data from a total of 123,867 individuals were included in the study. These included the total number of ANC attendances per woman and GA at first and last ANC contact. The GA determination practices of each clinic were also recorded. Results: Across all sites, women had a median of 4 ANC contacts per pregnancy (IQR 2-5). An estimated 79·2% of women had at least one ANC contact during the 24-36-week GA window, falling to 66·6% in a 28-36 week GA window, and 46·5% at 32-36 weeks. When stratified by ANC contact frequency, the proportion with at least one contact in 24-36 weeks increased to 94·1% among women with ≥4 ANC contacts, indicating significantly greater vaccine delivery potential among those with more frequent ANC contacts. Conclusion: In these LMIC settings, the 24-36-week GA window presents opportunity for delivering maternal vaccination at high coverage. These findings underscore the need to align maternal vaccine delivery strategies with real-world ANC patterns to ensure equitable and timely vaccine access in LMICs.

Identifiers

PMID41341283
PMCPMC12670892

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.