Evidence map›Paper›PMID 41341237›Full record

ArticleEuropean heart journal. Imaging methods and practice2025

The strain-8 study: a multimodal scan-rescan assessment of myocardial strain repeatability.

Andrew Bell, Joseph Okafor, Momina Yazdani, Russell Franks, Jane Draper, Brian Campbell, Stamatis Kapetanakis, Amedeo Chiribiri, Alistair Young, Muhummad Sohaib Nazir

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In one paragraph

Article in European heart journal. Imaging methods and practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Andrew BellSchool of Biomedical Engineering and Imaging Sciences, King's College London, 5th Floor, Beckett House, 1 Lambeth Palace Road, London SE1 7EU, UK.ORCID https://orcid.org/0009-0005-2560-8172
Joseph OkaforNational Heart and Lung Institute, Imperial College London, London, UK.ORCID https://orcid.org/0000-0002-1021-6134
Momina YazdaniNational Heart and Lung Institute, Imperial College London, London, UK.ORCID https://orcid.org/0000-0002-1776-8070
Russell FranksSchool of Biomedical Engineering and Imaging Sciences, King's College London, 5th Floor, Beckett House, 1 Lambeth Palace Road, London SE1 7EU, UK.
Jane DraperDepartment of Cardiology, Guys and St Thomas Hospital, London, UK.
Brian CampbellDepartment of Cardiology, Guys and St Thomas Hospital, London, UK.
Stamatis KapetanakisDepartment of Cardiology, Guys and St Thomas Hospital, London, UK.
Amedeo ChiribiriSchool of Biomedical Engineering and Imaging Sciences, King's College London, 5th Floor, Beckett House, 1 Lambeth Palace Road, London SE1 7EU, UK.ORCID https://orcid.org/0000-0003-3394-4289
Alistair YoungSchool of Biomedical Engineering and Imaging Sciences, King's College London, 5th Floor, Beckett House, 1 Lambeth Palace Road, London SE1 7EU, UK.ORCID https://orcid.org/0000-0001-5702-4220
Muhummad Sohaib NazirSchool of Biomedical Engineering and Imaging Sciences, King's College London, 5th Floor, Beckett House, 1 Lambeth Palace Road, London SE1 7EU, UK.ORCID https://orcid.org/0000-0003-2749-1033

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Aims: Myocardial strain is a powerful, non-invasive diagnostic and prognostic marker in patients with heart disease. However, its applicability is hindered by uncertain repeatability, particularly for segmental values. This study measures the repeatability of myocardial strain across eight imaging methods. Methods and results: In this prospective study, 20 healthy volunteers (aged 34 Results: Inter-scan repeatability of global strains ranged from excellent to fair (CoV ≤ 20%) depending on protocol. Using CMR feature tracking at 1.5T, relative global longitudinal strain (GLS) changes exceeding 11.2% are unlikely to be caused by measurement variability alone; this figure is 5.5% for 2D echocardiography. Segmental strain values frequently had poor repeatability (CoV > 20%), particularly for longitudinal and radial strains. Conclusion: Imaging protocols including CMR and Echo can measure global strain parameters with fair repeatability, but segmental strain values are unreliable. Future work should aim to improve the repeatability of segmental strain values, particularly longitudinal strain.

Identifiers

PMID41341237
PMCPMC12671395

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.