ReviewJournal of inflammation research2025
Targeting PANoptosis in Bacterial-Induced Inflammatory Diseases: Mechanisms and Therapeutic Interventions.
Review in Journal of inflammation research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Role of PANoptosis in the development of gastric immunity and related gastric mucosal disease (Review).Molecular medicine reports · 2026Review
- Advances in the molecular pathogenesis ofFrontiers in cellular and infection microbiology · 2026Review
- Gasdermin D-driven pyroptosis in sepsis: mechanisms, therapeutic strategies, and clinical translation.Frontiers in immunology · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
PANoptosis is a novel form of cell death that integrates necroptosis, apoptosis, and pyroptosis, along with their crosstalk, mediated and regulated by the PANoptosome. This review focuses on bacterial PANoptosis, systematically summarizing through distinct pathways and virulence factors, and analyzing its role in inflammatory diseases. Furthermore, we discuss potential therapeutic interventions related to PANoptosis in bacterial inflammation, establishing a framework for novel anti-inflammatory drug development. Understanding the mechanisms of bacteria-induced PANoptosis may provide new strategies for targeted intervention in inflammatory responses to infection.
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Registered trials
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