Evidence map›Paper›PMID 41341095›Full record

ArticleProceedings (Baylor University. Medical Center)2025

A rare cause of neonatal cholestasis: congenital portosystemic shunt.

Rıdvan Turhan, Nezihe Köker, Seda Aydoğan, Asuman Nur Karhan, Hasibe Gökçe Çınar

Abstract readCase Reports
In one paragraph

Article in Proceedings (Baylor University. Medical Center), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Rıdvan TurhanDepartment of Pediatrics, Inonu University, Türkiye.ORCID https://orcid.org/0009-0004-2962-7250
Nezihe KökerDepartment of Pediatrics, Inonu University, Türkiye.ORCID https://orcid.org/0000-0002-3962-9397
Seda AydoğanDepartment of Pediatrics, Newborn Unit, Ankara Etlik City Hospital, Ankara, Türkiye.ORCID https://orcid.org/0000-0002-6144-4225
Asuman Nur KarhanDepartment of Pediatrics, Pediatric Gastroenterology, Ankara Etlik City Hospital, Ankara, Türkiye.ORCID https://orcid.org/0000-0003-1665-4255
Hasibe Gökçe ÇınarDepartment of Radiology, Pediatric Radiology Clinic, Ankara Etlik City Hospital, Ankara, Türkiye.ORCID https://orcid.org/0000-0003-2687-1544

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Neonatal cholestasis is a pathological condition characterized by impaired bile flow in infants, typically presenting within the first 3 months of life. While common etiologies include biliary atresia, metabolic disorders, and infections, rare causes such as congenital portosystemic shunts must also be considered in the differential diagnosis. We present the case of a term infant with a congenital portosystemic shunt who presented with cholestasis and hyperammonemia. Bilirubin and liver function enzymes gradually decreased after initiation of ursodeoxycholic acid therapy. In newborns presenting with hypoglycemia, cholestasis, and thrombocytopenia, initial investigations are usually performed for metabolic diseases, congenital infections (toxoplasmosis, cytomegalovirus, rubella, herpes simplex virus), and genetic causes. As these tests may take time to return, early radiological imaging should be pursued to evaluate for anatomical abnormalities.

Indexed as

Cholestasiscongenital portosystemic shuntlivernewborn

Identifiers

PMID41341095
PMCPMC12671503

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.