Evidence map›Paper›PMID 41341082›Full record

ReviewProceedings (Baylor University. Medical Center)2025

Barriers and facilitators to recruitment of rural patients to cancer clinical trials.

Ruhi Thapar, Rebecca Mulley, Nathaniel Ferriola, Tiffany Luan, Richard Sanker, Lucas Wong, Erika L Abel, Lisa Go

Abstract readReview
In one paragraph

Review in Proceedings (Baylor University. Medical Center), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Ruhi ThaparDepartment of Student Affairs, Baylor College of Medicine, Houston, Texas, USA.ORCID https://orcid.org/0009-0008-2269-7810
Rebecca MulleyDepartment of Student Affairs, Baylor College of Medicine, Houston, Texas, USA.
Nathaniel FerriolaDepartment of Student Affairs, Baylor University, Waco, Texas, USA.
Tiffany LuanMary Crowley Cancer Research, Dallas, Texas, USA.
Richard SankerDepartment of Student Affairs, Baylor University, Waco, Texas, USA.
Lucas WongMedical Oncology, Baylor Scott & White Medical Center - Temple, Temple, Texas, USA.
Erika L AbelDepartment of Student Affairs, Baylor University, Waco, Texas, USA.
Lisa GoDepartment of Student Affairs, Baylor University, Waco, Texas, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Rural patients are significantly underrepresented in cancer clinical trials. A proper understanding of the barriers and facilitators to rural patient participation in cancer clinical trials is essential, especially in states like Texas where rural-urban disparity is prominent. Methods: EBSCO Medline, Embase, CINAHL, Cochrane, and PsycInfo were systematically searched for articles. A total of 2663 articles were screened, yielding 20 articles for study. Results: A systematic review of the literature revealed that barriers and facilitators to cancer clinical trial participation by rural populations are present at the patient, physician, and healthcare system levels. Notable barriers found in this review include the burden of travel, lack of patient knowledge about clinical trial participation, insufficient provider communication and awareness of current trials, and strict eligibility criteria. Promising facilitators include caregiver support, close physician support and contact, and programs to increase patient understanding of clinical trials. Conclusion: Further elucidating barriers to ascertain why rural patients have less participation in clinical trials, and exploring which facilitators need to be further explored, could allow for effectively harnessing the power of facilitators in the pursuit of lessening disparities and improving cancer outcomes for rural patients.

Indexed as

Adherencecancer clinical trialsrecruitmentruralurban

Identifiers

PMID41341082
PMCPMC12671508

What OpenQuestion holds

Textmetadata
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.