Evidence map›Paper›PMID 41341020›Full record

ArticleRadiologia brasileira

Can hydration protect against intravenous contrast-induced acute kidney injury?

Cassiane Dezoti da Fonseca, Dayse Santana Santos, Eduesley Santana Santos, Clara Versolato Razvickas, Bianca Castino, Fernanda Teixeira Borges, Maria de Fatima Fernandes Vattimo

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Article in Radiologia brasileira. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

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No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Cassiane Dezoti da FonsecaUniversidade Federal de São Paulo (Unifesp), São Paulo, SP, Brazil.ORCID 0000-0002-2118-8562
Dayse Santana SantosUniversidade Federal de São Paulo (Unifesp), São Paulo, SP, Brazil.ORCID 0000-0003-1483-5570
Eduesley Santana SantosUniversidade Federal de Sergipe (UFS), São Cristóvão, SE, Brazil.ORCID 0000-0001-8545-5677
Clara Versolato RazvickasUniversidade Federal de São Paulo (Unifesp), São Paulo, SP, Brazil.ORCID 0000-0002-5077-7956
Bianca CastinoUniversidade Federal de São Paulo (Unifesp), São Paulo, SP, Brazil.ORCID 0000-0002-6410-8817
Fernanda Teixeira BorgesUniversidade Federal de São Paulo (Unifesp), São Paulo, SP, Brazil.ORCID 0000-0002-9790-0915
Maria de Fatima Fernandes VattimoUniversidade de São Paulo (USP), São Paulo, SP, Brazil.ORCID 0000-0002-7036-5676

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Objective: To evaluate the effect of saline hydration on contrast-induced acute kidney injury in a rat model of diabetes mellitus. Materials and Methods: This was a quantitative, preclinical experimental study. A total of 28 male Wistar rats were randomized into four groups: citrate (control); diabetes mellitus-only; diabetes mellitus + iodinated contrast (6 mL/kg iothalamate meglumine); and diabetes mellitus + iodinated contrast + saline (NaCl 0.9%, 12 mL/kg). Physiological parameters, renal hemodynamics, inulin clearance (as a proxy for renal function), urinary albumin, and oxidative injury were assessed. Statistical significance was set at Conclusion: Saline hydration attenuated the impairment of renal function and hemodynamics by reducing redox imbalance in contrast-induced acute kidney injury.

Indexed as

Contrast mediaDiabetes mellitusKidney diseases/chemically inducedKidney/drug effectsPrimary preventionRisk factors

Identifiers

PMID41341020
PMCPMC12671852

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.