Evidence map›Paper›PMID 41340894›Full record

ArticleThe journal of medicine access

Essential medicines in Central America: Analysis of national lists, macroeconomic factors, and alignment with health priorities.

Ernesto Martínez-Vargas, Sebastian Arguedas-Chacón, Valeria González-Rodríguez, Jeaustin Mora-Jiménez, Kevin Cruz-Mora, Esteban Zavaleta-Monestel

Abstract read
In one paragraph

Article in The journal of medicine access. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ernesto Martínez-VargasPharmacy Department, Hospital Clínica Bíblica, San José, Costa Rica.ORCID https://orcid.org/0000-0002-5459-7370
Sebastian Arguedas-ChacónInvestigation Department, Hospital Clínica Bíblica, San José, Costa Rica.ORCID https://orcid.org/0000-0001-8547-7745
Valeria González-RodríguezSchool of Pharmacy, Universidad de Ciencias Médicas, San José, Costa Rica.
Jeaustin Mora-JiménezPharmacy Department, Hospital Clínica Bíblica, San José, Costa Rica.ORCID https://orcid.org/0009-0001-0543-2262
Kevin Cruz-MoraFaculty of Pharmacy, Universidad de Costa Rica, San José, Costa Rica.ORCID https://orcid.org/0009-0006-7272-1642
Esteban Zavaleta-MonestelInvestigation Department, Hospital Clínica Bíblica, San José, Costa Rica.ORCID https://orcid.org/0000-0003-3726-0079

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Introduction: The World Health Organization (WHO) Model List of Essential Medicines guides countries in selecting priority drugs to ensure equitable access to effective treatments. In regions such as Central America, with similar health and socioeconomic contexts, comparing national lists reveals patterns and opportunities for regional harmonization. Methodology: A cross-sectional comparative observational study was conducted using public secondary data from the official essential medicines lists of seven Central American countries: Belize, Costa Rica, El Salvador, Guatemala, Honduras, Nicaragua, and Panama. These lists were compared against the 2017 WHO Model List. Therapeutic classification was based on the Anatomical, Therapeutic, and Chemical Classification (ATC) system (level 2). Macroeconomic variables, including health expenditure per capita and gross domestic product (GDP) per capita, were analyzed for their relationship with list composition. Results: Panama had the most extensive NEML (570 drugs) and Nicaragua the shortest (271 drugs). Nicaragua showed the highest alignment with the WHO list, while Panama had the most exclusive drugs. A significant positive correlation was found between health expenditure per capita and NEML size ( Conclusion: Although Central American countries share regional similarities, their selection of essential medicines varies considerably. These differences reflect diverse public health priorities, institutional capacities, and economic conditions. The findings support the need for evidence-based, context-sensitive approaches and underscore the potential for regional cooperation in essential medicines policy.

Indexed as

access to medicinesCentral AmericaEssential medicinesnational listsselection of medicines

Identifiers

PMID41340894
PMCPMC12669477

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.