Evidence map›Paper›PMID 41340834›Full record

ArticleJournal of contemporary brachytherapy2025

Clinical and dosimetric outcomes of carcinoma cervix patients treated with MRI only at first fraction, followed by CT-based image-guided brachytherapy for subsequent fractions.

Madhup Rastogi, Ajeet Kumar Gandhi, Avinash Poojari, Vachaspati Mishra, Tenzing Dahla Bhutia, Rakhi Verma, Deepika Ramola, Rohini Khurana, Anoop K Srivastava, Pravin Kumar Das and 3 more

Abstract read
In one paragraph

Article in Journal of contemporary brachytherapy, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors.

Madhup RastogiDepartment of Radiation Oncology, Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknow, India.
Ajeet Kumar GandhiDepartment of Radiation Oncology, Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknow, India.
Avinash PoojariDepartment of Radiation Oncology, Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknow, India.
Vachaspati MishraDepartment of Radiation Oncology, Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknow, India.
Tenzing Dahla BhutiaDepartment of Radiation Oncology, Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknow, India.
Rakhi VermaDepartment of Radiation Oncology, Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknow, India.
Deepika RamolaDepartment of Radiation Oncology, Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknow, India.
Rohini KhuranaDepartment of Radiation Oncology, Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknow, India.
Anoop K SrivastavaDepartment of Radiation Oncology, Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknow, India.
Pravin Kumar DasDepartment of Anesthesiology, Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknow, India.
Abhishek ChauhanDepartment of Obstetrics and Gynecology, Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknow, India.
Neetu SinghDepartment of Obstetrics and Gynecology, Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknow, India.
Anurag GuptaDepartment of Pathology, Dr Ram Manohar Lohia Institute of Medical Sciences, Lucknow, India.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Purpose: Magnetic resonance (MRI)-based image-guided brachytherapy (IGBT) is the gold standard technique for carcinoma cervix. We aimed to evaluate doses to target and organs at risk (OARs), and report clinical outcomes of locally advanced carcinoma cervix (LACC) patients treated with a hybrid approach of using MRI- and computed tomography (CT)-based IGBT. Material and methods: Twenty-two LACC patients, after receiving external beam radiotherapy of 50 Gy in 25 fractions with concurrent cisplatin 40 mg/m Results: The median age was 50 years. Fourteen (63.6%) patients were FIGO (2010) stage II. HR-CTV volumes (mean ±SD) of MRI, CT-1, and CT-2 were 24.23 cc ±9.26 cc, 27.82 cc ±15.37 cc, and 24.82 cc ±11.14 cc, respectively ( Conclusions: Hybrid approach in IGBT using MRI at first fraction and CT for subsequent fractions yields comparable dosimetric parameters and decent long-term clinical outcomes. This approach could be considered resource-sparing brachytherapy technique.

Indexed as

carcinoma cervixCT-based IGBTimage-guided brachytherapy

Identifiers

PMID41340834
PMCPMC12669827

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